| Preserved autonomic function in patients with POEMS syndrome. | |
| | |
MedLine Citation:
|
PMID: 22507753 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
AIM: We systematically performed autonomic testing on patients with polyneuropathy, organomegaly, endocrinopathy, M-protein and skin changes syndrome (POEMS) to determine whether autonomic function is preserved in such patients. METHODS: We studied 17 POEMS patients, 17 diabetic neuropathy (DN) patients and 17 age-matched normal subjects. Blood pressure responses to the head-up tilt test and heart rate variability were used to evaluate cardiovascular autonomic function. Sweat responses and cutaneous vasoconstriction to several stimuli were recorded via the finger tips to estimate cutaneous sympathetic function. In addition, motor nerve conduction studies were performed. RESULTS: Although the results of the autonomic testing were normal in POEMS patients, motor disability was severe, and motor nerve conduction studies provided evidence of extensive axonal loss. The DN patients showed significantly impaired autonomic responses despite mild motor dysfunction. CONCLUSIONS: Autonomic function was normal in POEMS patients, indicating the preservation of autonomic fibers and selective involvement of large fibers. |
| | |
Authors:
|
Y Fujinuma; M Asahina; T Fukushima; A Katagiri; Y Yamanaka; S Misawa; S Kuwabara |
Related Documents
:
|
21532293 - Qt dispersion in patients with rheumatic mitral stenosis and its relation with echocard... 21549393 - Headache among mesial temporal lobe epilepsy patients: a case-control study. 7562753 - The use of single photon emission computerized tomography in neuropsychiatric sle: a pi... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-4-14 |
Journal Detail:
|
Title: Journal of the neurological sciences Volume: - ISSN: 1878-5883 ISO Abbreviation: - Publication Date: 2012 Apr |
Date Detail:
|
Created Date: 2012-4-17 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0375403 Medline TA: J Neurol Sci Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2012 Elsevier B.V. All rights reserved. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of e...
Next Document: No evidence for the 'expensive-tissue hypothesis' from an intraspecific study in a highly variable s...