| Preservation of high regional blood flow at epicardial rim after coronary occlusion in dogs. | |
| | |
MedLine Citation:
|
PMID: 8067406 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A thin myocardial layer adjacent to the epicardium (epicardial rim) often survives after transmural myocardial infarction. Regional myocardial blood flow (Qm) at this rim may be high enough to maintain myocardial viability during coronary occlusion. To test this hypothesis, we measured Qm in 12 anesthetized dogs during left anterior descending coronary artery occlusion using nonradioactive colored microspheres. Myocardium in the region supplied by the occluded artery was sliced into sections approximately 0.5 mm thick from the epicardial surface to the endocardium, and the Qm in each section was determined. During occlusion, the Qm of myocardium within 0.5 mm of the epicardial surface remained at 74.8 +/- 8.8% of the preocclusion level. Maintenance of this high Qm during occlusion was abolished when an epicardial incision approximately 1 mm deep was made around the occluded area. These findings suggest that Qm is maintained at a surprisingly high level at the epicardial rim after coronary occlusion through epicardial arterial communications, which may be sufficient to maintain myocardial viability. |
| | |
Authors:
|
K Ishikawa; N Kamata; S Nakai; H Akiyama; H Koka; I Ogawa; R Katori |
Related Documents
:
|
7307026 - Evolution of epicardial r wave voltage following experimental coronary artery occlusion... 19073306 - Endovascular management of subacute lower extremity ischemia. 18953746 - Effects of temporary clipping during aneurysm surgery. 12160256 - What types of occlusal factors play a role in temporomandibular disorders...? a literat... 21757816 - Cardiac magnetic resonance imaging-derived pulmonary artery distensibility index correl... 12683586 - Obstructive pneumonia: an indication for surgery in mega aorta syndrome. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: The American journal of physiology Volume: 267 ISSN: 0002-9513 ISO Abbreviation: Am. J. Physiol. Publication Date: 1994 Aug |
Date Detail:
|
Created Date: 1994-09-21 Completed Date: 1994-09-21 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0370511 Medline TA: Am J Physiol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: H528-34 Citation Subset: IM |
Affiliation:
|
First Department of Medicine, Kinki University School of Medicine, Osaka, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Arterial Occlusive Diseases / physiopathology* Collateral Circulation Coronary Circulation* Coronary Disease / physiopathology* Dogs Hemodynamics Microspheres Pericardium / physiopathology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: The blood pressure buffering capacity of nitric oxide by comparison to the baroreceptor reflex.
Next Document: Changes in regional vascular capacitance during prostacyclin-induced cardiac vagal reflex in pigs.