Document Detail

Preservation of cranial nerve function after radiosurgery for nonacoustic schwannomas.
MedLine Citation:
PMID:  8232798     Owner:  NLM     Status:  MEDLINE    
Microsurgical resection is the primary management approach for patients with intracranial schwannomas. Recent studies have demonstrated that stereotactic radiosurgery is an effective therapeutic modality for patients with acoustic schwannomas. To define the role of radiosurgery in the management of patients with nonacoustic schwannomas, we reviewed the results of gamma unit stereotactic radiosurgery in six patients with trigeminal and five patients with jugular foramen region schwannomas. No patient with a trigeminal schwannoma demonstrated tumor growth during a mean follow-up of 21 months (range, 7-35 mo), whereas one patient with a jugular foramen region schwannoma had an increase in tumor size 7 months after radiosurgery. No new cranial nerve or brain stem deficits were noted in either patient group after radiosurgery. In this early experience, radiosurgery proved an effective primary or adjuvant technique for selected patients with schwannomas of the trigeminal, glossopharyngeal, or vagus nerves. Using our described method, the safety of radiosurgery was demonstrated on the brain stem, regional cranial nerves, and especially those cranial nerves intimately associated with the tumor.
B E Pollock; D Kondziolka; J C Flickinger; A Maitz; L D Lunsford
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Neurosurgery     Volume:  33     ISSN:  0148-396X     ISO Abbreviation:  Neurosurgery     Publication Date:  1993 Oct 
Date Detail:
Created Date:  1993-12-17     Completed Date:  1993-12-17     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7802914     Medline TA:  Neurosurgery     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  597-601     Citation Subset:  IM    
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pennsylvania.
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MeSH Terms
Cranial Nerve Neoplasms / diagnosis,  surgery*
Follow-Up Studies
Glossopharyngeal Nerve / pathology,  surgery*
Jugular Veins / pathology,  surgery
Magnetic Resonance Imaging
Neoplasm Recurrence, Local / pathology,  surgery
Neurilemmoma / diagnosis,  surgery*
Neurologic Examination
Postoperative Complications / etiology
Tomography, X-Ray Computed
Trigeminal Nerve / pathology,  surgery*
Vagus Nerve / pathology,  surgery*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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