Document Detail


Presenting signs and symptoms of pheochromocytoma in pediatric-aged patients.
MedLine Citation:
PMID:  16211197     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
To describe the varied presenting signs and symptoms in pediatric patients with pheochromocytoma, a retrospective chart review of the presenting signs and symptoms and subsequent clinical course of patients who presented to the Pediatric ICU following surgical excision of a pheochromocytoma was undertaken. The cohort of 7 patients (5 boys, 2 girls) ranged in age from 4 to 16 years. Two patients were hypertensive at initial presentation, and the other 5 developed hypertension after their initial presentation. The initial presenting signs and symptoms were related to the central nervous system (CNS) in 6 of the patients (5 with an acute alteration in mental status and 1 with visual disturbances). Two patients presented with congestive heart failure. Other signs and symptoms at the time of initial presentation included sweating, headache, weight loss, heat intolerance, increased thirst and urination, a decline in school activity, and red/puffy hands and feet. The time from the initial presentation until the diagnosis was confirmed was 5 months or more in 4 of the 7 patients. The diagnosis was confirmed by demonstration of elevated urinary catecholamines in all 7 patients, although 2 patients had initial negative urinary levels.
Authors:
Janet Sullivan; Ted Groshong; Joseph D Tobias
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical pediatrics     Volume:  44     ISSN:  0009-9228     ISO Abbreviation:  Clin Pediatr (Phila)     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-10-07     Completed Date:  2006-03-21     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372606     Medline TA:  Clin Pediatr (Phila)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  715-9     Citation Subset:  AIM; IM    
Affiliation:
University of Missouri School of Medicine, Columbia, Missouri 65212, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adrenal Gland Neoplasms / complications,  diagnosis*,  surgery
Catecholamines / urine
Child
Child, Preschool
Diagnosis, Differential
Female
Headache / etiology
Heart Failure / etiology
Humans
Magnetic Resonance Imaging
Male
Pheochromocytoma / complications,  diagnosis*,  surgery
Retrospective Studies
Sweating
Syncope / etiology
Tomography, X-Ray Computed
Treatment Outcome
Chemical
Reg. No./Substance:
0/Catecholamines

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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