| Presentation and survival of patients with AIDS-related Kaposi's sarcoma in Jos, Nigeria. | |
| | |
MedLine Citation:
|
PMID: 19451327 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
AIDS-related Kaposi's sarcoma (AIDS-KS) remains a significant cause of morbidity and mortality. We describe the pattern of presentation and survival in Jos, Nigeria. We identified 48 HIV-positive patients with AIDS-KS and matched them for age and sex with an equal number of HIV-positive patients without AIDS-KS. We compared their clinical, immunological, virological characteristics and survival. They were similar in age and body mass index profile but patients with AIDS-KS had more tuberculosis co-infection (P, 0.02), lower median CD4 count (P, 0.003) and higher mortality (P, 0.002). Surprisingly, patients with AIDS-KS had lower levels of median viral load (29,347 copies/mL) compared with controls (80,533 copies/mL). We recommend specific AIDS-KS therapy in addition to highly active antiretroviral therapy in order to improve survival. |
| | |
Authors:
|
P A Agaba; H M Sule; R O Ojoh; Z Hassan; L Apena; M A Mu'azu; B Badung; O O Agbaji; J A Idoko; P Kanki |
Related Documents
:
|
3261737 - Pneumocystis carinii antigenemia in acquired immunodeficiency syndrome. 3918187 - Immune status of blood product recipients. 18333287 - Progression of kaposi sarcoma associated with iatrogenic cushing syndrome in a person w... 2413137 - Recovery of aids-associated retroviruses from patients with aids or aids-related condit... 17601007 - Prevention of hiv and other stis in rural senegal: a study of prevention-related events... 17358077 - Protection of oligonucleotides against enzymatic degradation by pegylated and nonpegyla... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: International journal of STD & AIDS Volume: 20 ISSN: 0956-4624 ISO Abbreviation: Int J STD AIDS Publication Date: 2009 Jun |
Date Detail:
|
Created Date: 2009-05-19 Completed Date: 2009-08-04 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9007917 Medline TA: Int J STD AIDS Country: England |
Other Details:
|
Languages: eng Pagination: 410-3 Citation Subset: IM; X |
Affiliation:
|
AIDS Prevention Initiative Nigeria (APIN) Centre, Jos University Teaching Hospital, Jos, Plateau State, Nigeria. ellagaba@yahoo.com |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
AIDS-Related Opportunistic Infections
/
epidemiology,
mortality*,
physiopathology Adult Antiretroviral Therapy, Highly Active Female HIV Infections / complications*, drug therapy, epidemiology, mortality* Humans Male Nigeria / epidemiology Sarcoma, Kaposi / complications, epidemiology, mortality*, physiopathology Survival Analysis Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Drug resistance in the Chinese National Pediatric Highly Active Antiretroviral Therapy Cohort: impli...
Next Document: To what extent does Neisseria gonorrhoeae multiantigen sequence typing of gonococcal isolates suppor...