| Present status of anticoagulation treatment in Japanese patients with atrial fibrillation: a report from the J-RHYTHM Registry. | |
| | |
MedLine Citation:
|
PMID: 21467664 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Underuse and an inadequate range for the international normalized ratio (INR) for warfarin use are still problems in the management of the patients with atrial fibrillation (AF) in Japan. METHODS AND RESULTS: From January to July 2009, a total of 7,937 AF patients [5,468 men (68.6 ± 10.0 years) and 2,469 women (72.2 ± 9.0 years)] were registered from 158 institutions for the J-RHYTHM Registry. Overall, 34.2% of the patients were over the age of 75. The associated cardiovascular diagnoses were hypertension in 59.1%, coronary artery disease in 10.1%, cardiomyopathy in 8.3%, valvular heart disease in 13.7% and artificial cardiac valves in 3.1% of the patients. The type of AF was paroxysmal in 37.1%, persistent in 14.4%, and permanent in 48.5%. Overall, 87.3% of patients were taking warfarin (2.9 ± 1.2mg/day), of whom 66.0% had an INR between 1.6 and 2.6, and 35.4% were in the INR range from 2.0 to 3.0 at the time of registration. Aspirin was prescribed in 22.3% of cases. The CHADS2 score was 0 in 15.7% of patients, 1 in 34.0%, and ≥ 2 in 50.3%. CONCLUSIONS: At present, warfarin is used extensively in patients with AF whose stroke risk is relatively low (ie, in Japan) and half of them had CHADS2 scores of 0 to 1 (UMIN Clinical Trials Registry UMIN000001569). |
| | |
Authors:
|
Hirotsugu Atarashi; Hiroshi Inoue; Ken Okumura; Takeshi Yamashita; Naoko Kumagai; Hideki Origasa; |
Related Documents
:
|
9489964 - Thyroid hormone and cardiovascular disease. 9435414 - Outcome of thyroid function in graves' patients treated with radioiodine: role of thyro... 8198334 - Increased incidence of thyroid cancer in patients with primary hyperparathyroidism: a c... 20696284 - Autoantibodies to parietal cells as predictors of atrophic body gastritis: a five-year ... 2184254 - Bladder volume determination using a dedicated, portable ultrasound scanner. 20454874 - Emergency management of acute ischemic stroke. |
Publication Detail:
|
Type: Journal Article; Multicenter Study Date: 2011-04-05 |
Journal Detail:
|
Title: Circulation journal : official journal of the Japanese Circulation Society Volume: 75 ISSN: 1347-4820 ISO Abbreviation: Circ. J. Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-05-26 Completed Date: 2011-09-16 Revised Date: 2012-01-09 |
Medline Journal Info:
|
Nlm Unique ID: 101137683 Medline TA: Circ J Country: Japan |
Other Details:
|
Languages: eng Pagination: 1328-33 Citation Subset: IM |
Affiliation:
|
Department of Internal Medicine, Nippon Medical School Tama-Nagayama Hospital, Tokyo, Japan. atarashi@nms.ac.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Anticoagulants / therapeutic use* Asian Continental Ancestry Group* Aspirin / therapeutic use Atrial Fibrillation / blood, complications, drug therapy*, ethnology Blood Coagulation / drug effects* Chi-Square Distribution Drug Monitoring / methods Female Fibrinolytic Agents / therapeutic use* Guideline Adherence Humans International Normalized Ratio Japan Male Middle Aged Platelet Aggregation Inhibitors / therapeutic use Practice Guidelines as Topic Prospective Studies Registries Risk Assessment Risk Factors Stroke / blood, ethnology, etiology, prevention & control* Treatment Outcome Warfarin / therapeutic use* |
| Chemical | |
Reg. No./Substance:
|
0/Anticoagulants; 0/Fibrinolytic Agents; 0/Platelet Aggregation Inhibitors; 50-78-2/Aspirin; 81-81-2/Warfarin |
| Investigator | |
Investigator/Affiliation:
|
H Inoue / ; K Okumura / ; H Atarashi / ; T Yamashita / ; M Sakurai / ; Y Kawamura / ; K Okumura / ; I Kubota / ; Y Kaneko / ; K Matumoto / ; S Ogawa / ; H Atarashi / ; T Yamashita / ; H Inoue / ; Y Aizawa / ; I Kodama / ; E Watanabe / ; Y Koretsune / ; Y Okuyama / ; A Shimizu / ; O Igawa / ; S Bando / ; M Fukatani / ; T Saikawa / ; A Chishaki / ; N Kumagai / ; H Origasa / ; N Kato / ; K Kanda / ; J Kato / ; H Obata / ; M Aoki / ; H Honda / ; Y Konta / ; T Hatayama / ; Y Abe / ; K Terata / ; T Yagi / ; A Ishida / ; T Komatsu / ; H Tachibana / ; H Suzuki / ; Y Kamiyama / ; T Watanabe / ; M Ogum / ; M Itoh / ; O Hirono / ; Y Tsunoda / ; K Ikeda / ; T Kanaya T / ; K Sakurai / ; H Sukekawa / ; S Nakada / ; T Itoh / ; S Tange / ; M Manita / ; M Ohta / ; H Eguma / ; R Kato / ; Y Endo / ; T Ogino / ; M Yamazaki / ; H Kanki / ; M Uchida / ; S Miyanaga / ; K Shibayama / ; N Toratani / ; T Kojima / ; M Ichikawa / ; M Saito / ; Y Umeda / ; T Sawanobori / ; H Sohara / ; S Okubo / ; T Okubo / ; T Tokunaga / ; O Kuboyama / ; H Ito / ; Y Kitahara / ; K Sagara / ; T Satoh / ; E Kodani / ; K Sugi / ; Y Kobayashi / ; Y Higashi / ; T Katoh / ; Y Hirayama / ; N Matsumoto / ; M Takano / ; T Ikeda / ; S Yusu / ; S Niwano / ; Y Nakazato / ; Y Kawano / ; M Sumiyoshi / ; N Hagiwara / ; K Murasaki / ; H Mitamura / ; S Nakagawa / ; K Okishige / ; K Azegami / ; H Aoyagi / ; K Sugiyama / ; M Nishizaki / ; N Yamawake / ; I Watanabe / ; K Ohkubo / ; H Sakurada / ; S Fukamizu / ; M Suzuki / ; W Nagahori / ; T Nakamura / ; Y Murakawa / ; N Hayami / ; K Yoshioka / ; M Amino / ; K Hirao / ; A Yagishita / ; K Ajiki / ; K Fujiu / ; Y Imai / ; A Yamashina / ; T Ishiyama / ; M Sakabe / ; K Nishida / ; H Asanoi / ; H Ueno / ; J-D Lee / ; Y Mitsuke / ; H Furushima / ; K Ebe / ; M Tagawa / ; M Sato / ; M Morikawa / ; K Yamashiro / ; K Takami / ; T Ozawa / ; M Watarai / ; M Yamauchi / ; H Kamiya / ; H Hirayama / ; Y Yoshida / ; T Murohara / ; Y Inden / ; H Osanai / ; N Ohte / ; T Goto / ; I Morishima / ; T Yamamoto / ; H Hayashi / ; T Urushida / ; Y Takada / ; R Kato / ; N Tsuboi / ; T Noda / ; T Hirose / ; H Izawa / ; A Sugiura / ; T Arakawa / ; K Kimura / ; T Mine / ; K Makita / ; H Shimizu / ; T Kurita / ; K Motoki / ; N Takeda / ; Y Kijima / ; M Ito / ; A Nakata / ; Y Ueda / ; A Hirata / ; S Kamakura / ; K Satomi / ; T Noda / ; Y Yamada / ; Y Yoshiga / ; H Ogawa / ; M Kimura / ; T Hayano / ; T Kinbara / ; H Tatsuno / ; M Harada / ; K F Kusano / ; M Adachi / ; A Yano / ; M Sawaguchi / ; J Yamasaki / ; T Matsuura / ; Y Tanaka / ; H Moritani / ; T Maki / ; S Okada / ; M Takechi / ; T Hamada / ; A Nishikado / ; Y Takagi / ; I Matsumoto / ; T Yamamoto / ; T Soeki / ; Y Doi / ; M Okawa / ; H Seo / ; S Kitamura / ; K Yamamoto / ; M Akizawa / ; N Kaname / ; S Ando / ; S Narita / ; T Nakamura / ; T Inou / ; Y Fukuizumi / ; K Saku / ; M Ogawa / ; Y Urabe / ; M Ikeuchi / ; S Harada / ; H Yamabe / ; Y Imamura / ; Y Yamanouchi / ; K Sadamatsu / ; K Yoshida / ; T Kubota / ; N Takahashi / ; N Makino / ; Y Higuchi / ; T Ooie / ; T Iwao / ; K Kitamura / ; T Imamura / ; K Maemura / ; N Komiya / ; M Hayano / ; H Yoshida / ; K Yamashiro / ; K Kumagai / |
| Comments/Corrections | |
Comment In:
|
Circ J. 2011;75(6):1314-5
[PMID:
21532184
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Soluble lectin-like oxidized low-density lipoprotein receptor-1 as an early biomarker for ST elevati...
Next Document: Acceleration of Ca2+ waves in monocrotaline-induced right ventricular hypertrophy in the rat.