| Presence of nonesterified and acylcarnitine in human polymorphonuclear leukocytes and mononuclear cells. | |
MedLine Citation:
|
PMID: 3829385 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We demonstrate the presence of nonesterified carnitine and acylcarnitine in leukocytes, but not in erythrocytes, from 16 healthy adults. After carefully separating the different kinds of blood cells we measured significant amounts of nonesterified carnitine and acylcarnitine in polymorphonuclear leukocytes (28.5 +/- 6.1 and 18.5 +/- 6.3 mumol/10(9) cells) and mononuclear cells (25.4 +/- 5.2 and 14.8 +/- 4.5 mumol/10(9) cells). We also measured nonesterified carnitine, long-chain acylcarnitine, and short-chain acylcarnitine in plasma after fractionation with perchloric acid and obtained the following values (mean +/- SD): 41.4 +/- 2.6, 3.9 +/- 1.2, and 6.0 +/- 1.6 mumol/L, respectively. The mean percentages of total carnitine (n = 6) in polymorphonuclear leukocytes, mononuclear cells, and plasma were approximately 62%, 27%, and 13% of whole-blood carnitine, respectively (mean recovery was 102%). The percentage of acylated carnitine was 37% in leukocytes, as compared with 19% in plasma. |
Authors:
|
K Katrib; H A Adlouni; G Férard |
Related Documents
:
|
24381195 - How to make a primordial germ cell. 23700305 - 2,3,7,8-tetrachlorodibenzo-p-dioxin modulates estradiol-induced aldehydic dna lesions i... 24726915 - Ankhd1, a novel component of the hippo signaling pathway, promotes yap1 activation and ... 24486015 - The role of the gap junction protein connexin43 in b lymphocyte motility and migration. 15779865 - The change of intracellular ph is involved in the cisplatin-resistance of human lung ad... 8094625 - Immunopathogenesis, diagnosis, and treatment of giant cell arteritis, temporal arteriti... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Clinical chemistry Volume: 33 ISSN: 0009-9147 ISO Abbreviation: Clin. Chem. Publication Date: 1987 Apr |
Date Detail:
|
Created Date: 1987-05-18 Completed Date: 1987-05-18 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 9421549 Medline TA: Clin Chem Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 533-5 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Acylation Carnitine / blood* Energy Metabolism Esters / blood Humans Monocytes / analysis* Neutrophils / analysis* |
| Chemical | |
Reg. No./Substance:
|
0/Esters; 541-15-1/Carnitine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Indirect vs direct measurement of magnesium and zinc in erythrocytes.
Next Document: Radioimmunoassay of somatomedin-C in filter paper discs containing dried blood.