Prescriptions for category D and X drugs during pregnancy in Taiwan: a population-based study. | |
MedLine Citation:
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PMID: 24578346 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: This study aimed to investigate the most prescribed medications and principle diagnoses for category D and X drugs during pregnancy using a population-based dataset in Taiwan. METHODS: The data for the present study were sourced from the Taiwan Longitudinal Health Insurance Database 2000. We selected 14 125 women who had live singleton births between 1 January 2009 and 31 December 2011. In total, 217 226 prescriptions prescribed to these pregnant women were identified. RESULTS: Of the total 217 226 prescriptions, 1.1% were category D or X drugs; in the first, second, and third trimesters of pregnancy, 1.8%, 0.7%, and 0.5% of prescriptions were category D or X drugs, respectively. Progestins (15.3%) and propylthiouracil (10.7%) were the two most frequently prescribed category D or X drugs during pregnancy. In particular, progestins (20.4%) and estrogens (15.6%) were the most frequently prescribed category D or X drug in the first trimester of pregnancy. Propylthiouracil was the most prescribed category D or X drug in the second (20.3%) and third trimesters (23.1%) of pregnancy, respectively. The most common principal diagnosis during pregnancy was "disorders of menstruation and other abnormal bleeding from the female genital tract" (22% of all principal diagnoses for prescribing category D and X drugs). CONCLUSIONS: Our study found that the physicians obviously reduced the use of category D and X drugs for women after becoming aware that they were pregnant. Copyright © 2014 John Wiley & Sons, Ltd. |
Authors:
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Li-Ting Kao; Yi-Hua Chen; Herng-Ching Lin; Shiu-Dong Chung |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2014-2-28 |
Journal Detail:
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Title: Pharmacoepidemiology and drug safety Volume: - ISSN: 1099-1557 ISO Abbreviation: Pharmacoepidemiol Drug Saf Publication Date: 2014 Feb |
Date Detail:
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Created Date: 2014-2-28 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9208369 Medline TA: Pharmacoepidemiol Drug Saf Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2014 John Wiley & Sons, Ltd. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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