| Prescription of twice-weekly hemodialysis in the USA. | |
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MedLine Citation:
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PMID: 10592355 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND/AIMS: The purpose of this study was to investigate the frequency and characteristics of two hemodialysis sessions/week, to identify factors which influence or predict this prescription, and to examine the outcomes of patients receiving hemodialysis two times/week as compared to the more common treatment of three times/week. METHODS: Data from a national sample of 15,067 adult hemodialysis patients were utilized to compare twice-weekly with thrice-weekly therapy by logistic regression. RESULTS: Patients treated less than one year were more likely to be treated twice-weekly (6.1%) than patients on dialysis for one year or more (2.7%) (AOR = 1.49, p = 0.002). Treatment schedules also varied significantly by geographic region. Factors predictive of twice-weekly hemodialysis (p < 0.05) were older age, Caucasian race, female gender, higher serum albumin, lower serum creatinine levels, and lower body mass index. A higher estimated renal function at the start of ESRD was also predictive of a twice-weekly schedule among incident patients (AOR = 1.05, p = 0.05). In addition, Cox-adjusted survival analysis indicated a lower mortality risk (RR = 0.76, p = 0. 02) for twice-weekly hemodialysis compared to thrice-weekly among prevalent patients. For incident patients, however, the results were not significant when adjusted for GFR at ESRD onset (RR = 0.85, p = 0.31). CONCLUSION: Geographic differences in prescribed treatment remained unexplained by measured characteristics. The survival advantage associated with twice-weekly hemodialysis is likely to be related to patient selection and greater residual renal function. |
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Authors:
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J A Hanson; T E Hulbert-Shearon; A O Ojo; F K Port; R A Wolfe; L Y Agodoa; J T Daugirdas |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial |
Journal Detail:
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Title: American journal of nephrology Volume: 19 ISSN: 0250-8095 ISO Abbreviation: Am. J. Nephrol. Publication Date: 1999 |
Date Detail:
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Created Date: 2000-01-20 Completed Date: 2000-01-20 Revised Date: 2009-12-30 |
Medline Journal Info:
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Nlm Unique ID: 8109361 Medline TA: Am J Nephrol Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 625-33 Citation Subset: IM |
Copyright Information:
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Copyright 1999 S. Karger AG, Basel |
Affiliation:
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University of Michigan, Ann Arbor 48103, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Female Humans Kidney Failure, Chronic / mortality, therapy* Male Middle Aged Prescriptions / statistics & numerical data* Prospective Studies Renal Dialysis / mortality, utilization* Risk Factors Survival Rate Treatment Outcome United States / epidemiology |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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