Document Detail

Prescription of atropine eye drops among children diagnosed with myopia in Taiwan from 2000 to 2007: a nationwide study.
MedLine Citation:
PMID:  23288141     Owner:  NLM     Status:  MEDLINE    
PURPOSE: This study was conducted to examine the atropine eye drop prescription trend for children diagnosed with myopia, and to determine the factors associated with the prescription of atropine eye drops.
DESIGN: This was a population-based cross-sectional study.
METHODS: This study was conducted using a national representative sample from the National Health Insurance (NHI) claims data. All school children between 4 and 18 years of age who had visited an ophthalmologist and were diagnosed with myopia between 2000 and 2007 were included herein. The main outcome measure was the proportion of subjects who were prescribed atropine eye drops in each year. Logistic regression was used to identify the factors associated with atropine eye drops being prescribed.
RESULTS: The prescription of atropine eye drops for children diagnosed with myopia increased significantly from the school years 2000 (36.9%) to 2007 (49.5%). There was also a shift from prescribing high concentrations (0.5 and 1%) of atropine eye drops to lower concentration ones (0.3, 0.25, and 0.1%) within this period. Atropine eye drops were more frequently prescribed to 9-12-year-old children (OR=1.26-1.42, compared with those 7-8 years old), and to children from families with a high socioeconomic status (OR=1.19-1.25); however, they were less prescribed to those living in mid to low urbanized areas (OR=0.65-0.84).
CONCLUSIONS: This study revealed an increasing trend of atropine eye drop prescription for children with myopia in Taiwan. Our study provides eye-care professionals worldwide a reference for the potential integration of atropine eye drops into their clinical practice toward children with myopia.
Y-T Fang; Y-J Chou; C Pu; P-J Lin; T-L Liu; N Huang; P Chou
Publication Detail:
Type:  Journal Article     Date:  2013-01-04
Journal Detail:
Title:  Eye (London, England)     Volume:  27     ISSN:  1476-5454     ISO Abbreviation:  Eye (Lond)     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-14     Completed Date:  2013-08-02     Revised Date:  2014-03-07    
Medline Journal Info:
Nlm Unique ID:  8703986     Medline TA:  Eye (Lond)     Country:  England    
Other Details:
Languages:  eng     Pagination:  418-24     Citation Subset:  IM    
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MeSH Terms
Atropine / administration & dosage*
Child, Preschool
Cross-Sectional Studies
Drug Prescriptions / statistics & numerical data*
Mydriatics / administration & dosage*
Myopia / drug therapy*,  epidemiology
National Health Programs / statistics & numerical data
Ophthalmic Solutions
Physician's Practice Patterns / statistics & numerical data*
Social Class
Taiwan / epidemiology
Urban Population / statistics & numerical data
Reg. No./Substance:
0/Mydriatics; 0/Ophthalmic Solutions; 7C0697DR9I/Atropine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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