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Prescribing patterns of low doses of antipsychotic medications in older Asian patients with schizophrenia, 2001-2009.
MedLine Citation:
PMID:  22300452     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
ABSTRACTBackground: This study examined the use of low doses of antipsychotic medications (300 mg/day CPZeq or less) in older Asian patients with schizophrenia and its demographic and clinical correlates.Methods: Information on hospitalized patients with schizophrenia, aged 55 years or older, was extracted from the database of the Research on Asian Psychotropic Prescription Patterns (REAP) study (2001-2009). Data on 1,452 patients in eight Asian countries and territories including China, Hong Kong, Japan, Korea, Singapore, Taiwan, India, and Malaysia were analyzed. Sociodemographic and clinical characteristics and antipsychotic prescriptions were recorded using a standardized protocol and data collection procedure.Results: The prescription frequency for low doses of antipsychotic medications was 40.9% in the pooled sample. Multiple logistic regression analysis of the whole sample showed that patients on low doses of antipsychotic medications were more likely to be female, have an older age, a shorter length of illness, and less positive symptoms. Of patients in the six countries and territories that participated in all the surveys between 2001 and 2009, those in Japan were less likely to receive low doses of antipsychotics.Conclusion: Low doses of antipsychotic medications were only applied in less than half of older Asian patients with schizophrenia.
Authors:
Yu-Tao Xiang; Faith Dickerson; Julie Kreyenbuhl; Gabor S Ungvari; Chuan-Yue Wang; Tian-Mei Si; Edwin H M Lee; Yan-Ling He; Helen F K Chiu; Kelly Y C Lai; Naotaka Shinfuku; Shu-Yu Yang; Mian-Yoon Chong; Ee-Heok Kua; Senta Fujii; Kang Sim; Michael K H Yong; Jitendra K Trivedi; Eun-Kee Chung; Pichet Udomratn; Kok-Yoon Chee; Norman Sartorius; Chay-Hoon Tan
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-3
Journal Detail:
Title:  International psychogeriatrics / IPA     Volume:  -     ISSN:  1741-203X     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-2-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9007918     Medline TA:  Int Psychogeriatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-7     Citation Subset:  -    
Affiliation:
Department of Psychiatry, Chinese University of Hong Kong, Hong Kong SAR, China.
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