Document Detail

Prescribing of nicotine replacement therapy to adolescents in England.
MedLine Citation:
PMID:  21466605     Owner:  NLM     Status:  MEDLINE    
AIMS: In November 2005, the indications for nicotine replacement therapy (NRT) were broadened in the United Kingdom, making all forms available to 12-17-year-olds. This study aimed to estimate the effects of this change on prescribing of NRT to adolescents in England.
DESIGN: Segmented regression analysis of primary care data on prescribing of nicotine replacement therapy using general additive mixed models.
SETTING: A total of 350 general practices in England included in The Health Improvement Network (THIN), a database of UK electronic primary care records.
PARTICIPANTS: All 12-17-year-old patients registered with a THIN practice in England. Measurements   Monthly rates of prescribing of NRT per 100 000 12-17-year-old patients registered with a THIN practice between January 2002 and June 2009.
FINDINGS: Prescribing of NRT was highest in 16-17-year-olds and extremely low in 12-13-year-olds, generally fewer than 10 prescriptions per 100 000 adolescents per month. Girls tended to be prescribed NRT more frequently than boys. In 12-17-year-olds rates of prescribing were increasing prior to the broadening of indications, and there was no step change, but the rate of increase was lower, after the indications were broadened.
CONCLUSIONS: Recent changes to the marketing licence for nicotine replacement therapy in England to include adolescents appear to have had little or no effect on prescribing practices.
Tessa E Langley; Yue Huang; Sarah Lewis; Ann McNeill; Tim Coleman; Lisa Szatkowski
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2011-06-01
Journal Detail:
Title:  Addiction (Abingdon, England)     Volume:  106     ISSN:  1360-0443     ISO Abbreviation:  Addiction     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-07-13     Completed Date:  2011-11-30     Revised Date:  2014-02-20    
Medline Journal Info:
Nlm Unique ID:  9304118     Medline TA:  Addiction     Country:  England    
Other Details:
Languages:  eng     Pagination:  1513-9     Citation Subset:  IM    
Copyright Information:
© 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.
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MeSH Terms
Databases, Factual
Drug Prescriptions / statistics & numerical data*
Family Practice
Medical Records Systems, Computerized
Nicotine / therapeutic use*
Nicotinic Agonists / therapeutic use*
Patient Acceptance of Health Care
Physician's Practice Patterns / statistics & numerical data*,  trends
Regression Analysis
Smoking / drug therapy*,  epidemiology
Smoking Cessation / statistics & numerical data*
Tobacco Use Cessation Products / statistics & numerical data,  utilization
Grant Support
G0701100//Medical Research Council; //British Heart Foundation; //Cancer Research UK; //Chief Scientist Office; //Department of Health; //Medical Research Council
Reg. No./Substance:
0/Nicotinic Agonists; 54-11-5/Nicotine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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