Document Detail

Prepulse rise time and startle reflex modification: different effects for discrete and continuous prepulses.
MedLine Citation:
PMID:  2727217     Owner:  NLM     Status:  MEDLINE    
The rise time of an auditory prepulse was varied to determine whether the onset transient of the prepulse is of primary importance in the modification of the acoustic startle reflex. In Experiment 1, 20-ms long discrete prepulses were presented at a lead time of 150 ms, and prepulse rise time was varied from 0.1 to 20 ms. Although all prepulses resulted in decreased response amplitude (inhibition of startle), varying rise time from 0.1 to 20 ms had no effect on reflex modification. These results suggest that the startle response is not sensitive to prepulse rise time changes in the range used here. In Experiment 2, continuous prepulses (in which lead time equals duration) were presented. Several of these prepulses had a lead time of 150 ms and rise times ranging from 0.1 to 150 ms, whereas others had a rise time of 0.1 ms and lead times of 50 to 150 ms. The results showed that only the fast-rising, 50-ms lead time prepulse decreased response amplitude, with the other prepulses having no effect on amplitude, relative to control responding. Rise time changes generally had no effect on responding, but responses were larger at longer lead times than at shorter lead times. Response probability was inhibited by fast-rising prepulses at lead times of 50 to 130 ms. Together with the results of Experiment 1, these findings suggest that startle reflex inhibition is determined by the onset of a prepulse, and that this inhibition is not sensitive to small changes in prepulse rise time.(ABSTRACT TRUNCATED AT 250 WORDS)
T D Blumenthal; B J Levey
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Psychophysiology     Volume:  26     ISSN:  0048-5772     ISO Abbreviation:  Psychophysiology     Publication Date:  1989 Mar 
Date Detail:
Created Date:  1989-06-23     Completed Date:  1989-06-23     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0142657     Medline TA:  Psychophysiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  158-65     Citation Subset:  IM    
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MeSH Terms
Reaction Time*
Sensory Thresholds
Startle Reaction*

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