| Preparative isolation and purification of salvianolic acid B from the Chinese medicinal plant Salvia miltiorrhiza by high-speed counter-current chromatography. | |
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MedLine Citation:
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PMID: 11833643 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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High-speed counter-current chromatography was applied to the isolation and purification of salvianolic acid B from the Chinese medicinal plant Salvia miltiorrhiza Bunge. The crude salvianolic acid B was obtained by extraction with ethanol-water from S. miltiorrhiza Bunge. Preparative high-speed counter-current chromatography with a two-phase solvent system composed of n-hexane-ethyl acetate-ethanol-water (3:7:1:9, v/v) was successfully performed yielding 342 mg salvianolic acid B at 98% purity from 500 mg of the crude extract in a one-step separation. |
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Authors:
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Hua-Bin Li; Jia-Ping Lai; Yue Jiang; Feng Chen |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of chromatography. A Volume: 943 ISSN: 0021-9673 ISO Abbreviation: J Chromatogr A Publication Date: 2002 Jan |
Date Detail:
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Created Date: 2002-02-08 Completed Date: 2002-07-24 Revised Date: 2009-01-15 |
Medline Journal Info:
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Nlm Unique ID: 9318488 Medline TA: J Chromatogr A Country: Netherlands |
Other Details:
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Languages: eng Pagination: 235-9 Citation Subset: IM |
Affiliation:
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Department of Botany, The University of Hong Kong, China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Benzofurans
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analysis,
isolation & purification* Chromatography, High Pressure Liquid Countercurrent Distribution / methods* Salvia / chemistry* |
| Chemical | |
Reg. No./Substance:
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0/Benzofurans; 115939-25-8/salvianolic acid B |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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