| Preparation of silver nanoparticles with antimicrobial activities and the researches of their biocompatibilities. | |
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MedLine Citation:
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PMID: 20652373 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Silver nanoparticles were prepared by chemical reduction method using chitosan as stabilizer and ascorbic acid as reducing agent in this work. The silver/chitosan nanocomposites were characterized in terms of their particle sizes and morphology by using UV spectrophotometer, nano-grainsize analyzer, and transmission electron microscopy. Antibacterial activities of these nanocomposites were carried out for Staphylococcus aureus and Escherichia coli. The silver nanoparticles exhibited significantly inhibition capacity towards these bacteria. Detailed studies on the biocompatibility of the silver/chitosan nanocomposites were investigated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay and cell adhesion test. The results indicated that these silver/chitosan nanocomposites were benefit for the proliferation and adhesion of L-929 cells, and the biocompatibilities between the nanocomposites and the cells would become better with the culturing days. We anticipated that these silver/chitosan nanocomposites could be a promising candidate as coating material in biomedical engineering and food packing fields wherein antibacterial properties and biocompatibilities are crucial. |
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Authors:
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X L Cao; C Cheng; Y L Ma; C S Zhao |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2010-07-22 |
Journal Detail:
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Title: Journal of materials science. Materials in medicine Volume: 21 ISSN: 1573-4838 ISO Abbreviation: J Mater Sci Mater Med Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9013087 Medline TA: J Mater Sci Mater Med Country: United States |
Other Details:
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Languages: eng Pagination: 2861-8 Citation Subset: IM |
Affiliation:
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College of Polymer Science and Engineering, State Key Laboratory of Polymer Materials Engineering, Sichuan University, ChengDu, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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