Document Detail

Preparation of a novel glucuronomannan from Auricularia auricala and its immunological activity.
MedLine Citation:
PMID:  23285818     Owner:  NLM     Status:  In-Process    
A glucuronomannan (AA-4-H, Mw around 4 KDa) was prepared from the fruit bodies of Auricularia auricala by extraction with hot water, deproteination by Sevag reagent, stepwise precipitation with ethanol and partial acid hydrolysis. Monosaccharides analysis revealed that AA-4-H consisted of 91% mannose (Man) and 9% glucuronic acid (GlcA). FT-IR, NMR and methylation analyses indicated that AA-4-H is a branched glucuronomannan. Its main chains are composed of 1, 3-linked alpha-Manp, side chains are single a-Manp or alpha-GlcA residues attached to the O-2 and O-6 of Man residues of the main chains. Bioassay indicated that AA-4-H remarkably enhanced B lymphocyte proliferation and increased the production of nitric oxide of macrophages in vitro. Thus, glucuronomannan AA-4-H could be explored as a potential immunostimulation agent.
Zonghong Li; Dan Jiang; Hongtao Bi; Dazheng Liu; Sungju Jang; Yifa Zhou
Related Documents :
22955678 - Myosin-cross-reactive antigens from four different lactic acid bacteria are fatty acid ...
11783638 - Characterization of secondary aerosol from the photooxidation of toluene in the presenc...
24838798 - Direct acid methylation for extraction of fatty acid content from microalgae cells.
15649018 - Synthesis of novel fluorogenic l-fmoc lysine derivatives as potential tools for imaging...
3980298 - Menaquinone composition of mycolic acid-containing actinomycetes and some sporoactinomy...
18965218 - Determination of nitric acid concentration by using europium ion fluorescence.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Natural product communications     Volume:  7     ISSN:  1934-578X     ISO Abbreviation:  Nat Prod Commun     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2013-01-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101477873     Medline TA:  Nat Prod Commun     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1507-10     Citation Subset:  IM    
School of Life Sciences, Northeast Normal University, Changchun 130024, PR China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Effect of 1,5-anhydro-D-fructose on the inhibition of adipogenesis in 3T3-L1 adipocytes.
Next Document:  Microwave-assisted isolation of essential oils from Nepeta crispa and N. racemosa and comparisons wi...