| Preparation of a new electrochemical sensor based on iron (III) complexes modified carbon paste electrode for simultaneous determination of mefenamic acid and indomethacin. | |
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MedLine Citation:
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PMID: 22192613 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A new chemically modified carbon paste electrodes based on Fe (III) schiff base (Fe (III)-SBMCP)-containing graphite pastes were prepared and evaluated as electrochemical sensor for the voltammetric determination of mefenamic acid and indomethacin in aqueous solutions. The measurements were carried out by application of the differential pulse voltammetry (DPV) method in phosphate buffer solution with pH 3.5. Fe (III) loaded in schiff base can increase anodic peak currents by adsorption of mefenamic acid and indomethacin on electrode surface. The prepared electrode shows voltammetric responses with high sensitivity for mefenamic acid and indomethacin in optimal conditions, which makes it very suitable for simultaneous determination of these compounds. The proposed method was successfully applied for determination mefenamic acid and indomethacin in commercial tablet samples. |
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Authors:
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Mohammad Hasanzadeh; Nasrin Shadjou; Lotfali Saghatforoush; Jafar Ezzati Nazhad Dolatabadi |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-8 |
Journal Detail:
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Title: Colloids and surfaces. B, Biointerfaces Volume: - ISSN: 1873-4367 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-23 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9315133 Medline TA: Colloids Surf B Biointerfaces Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier B.V. All rights reserved. |
Affiliation:
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Drug Applied Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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