Document Detail


Preparation of enantiomerically enriched α-aminoorganostannanes and their applications in stereoselective synthesis.
MedLine Citation:
PMID:  20845429     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This review deals with the preparation of chiral, nonracemic α-aminoorganostannanes and their applications in asymmetric synthesis. The pioneering works in this field date back almost 20 years ago and since then extensive research has been carried out to develop efficient and selective routes to highly enantioenriched α-aminoorganostannanes. The facile Sn/Li transmetalation of these compounds by n-BuLi has led to various applications in stereoselective synthesis. Selected examples using chiral α-aminoorganostannanes as starting materials will be reported.
Authors:
Vincent Coeffard; Isabelle Beaudet; Jean-Paul Quintard; Erwan Le Grognec
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Chirality     Volume:  22     ISSN:  1520-636X     ISO Abbreviation:  Chirality     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-09-27     Completed Date:  2011-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8914261     Medline TA:  Chirality     Country:  United States    
Other Details:
Languages:  eng     Pagination:  864-9     Citation Subset:  IM    
Copyright Information:
© 2010 Wiley-Liss, Inc.
Affiliation:
Université de Nantes, CNRS, Chimie et Interdisciplinarité: Synthèse, Analyse, Modélisation (CEISAM), UMR CNRS 6230, Faculté des Sciences et des Techniques, BP 92208, 44322 Nantes, Cedex 3, France.
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MeSH Terms
Descriptor/Qualifier:
Indicators and Reagents
Lithium / chemistry
Metals / chemistry
Organometallic Compounds / chemistry
Organotin Compounds / chemical synthesis,  chemistry*
Stereoisomerism*
Tin / chemistry*
Chemical
Reg. No./Substance:
0/Indicators and Reagents; 0/Metals; 0/Organometallic Compounds; 0/Organotin Compounds; 0/n-butyllithium; 7439-93-2/Lithium; 7440-31-5/Tin

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