Document Detail


Preparation of disodium fluorescein powders in association with lauric and capric acids.
MedLine Citation:
PMID:  14603518     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In previous studies micronized disodium fluorescein (DF) powders were coated with lauric or capric acid. This was a precursor to evaluating the effects of the fatty acids on the hygroscopic growth of the DF aerosols. Studies of the association of fatty acids with DF reflected a limited interpretation of the data obtained. The present study examines more closely the phenomena involved in coating the DF. It is concluded that lateral interactions due to the hydrophobic aliphatic tails of the fatty acids give rise to adsorption, aggregation, and flocculation, all of which cause inflections in the association isotherm rendering it nonlinear.
Authors:
D J Cooney; A J Hickey
Related Documents :
18391478 - Metabolism of odd-numbered fatty acids and even-numbered fatty acids in mouse.
445848 - Mechanisms of interference of nonesterified fatty acids in radioimmunoassays of steroids.
2026498 - Synthesis and biodistribution of a new class of 99mtc-labeled fatty acid analogs for my...
22014728 - Anti-inflammatory effects of fatty acids isolated from chromolaena odorata.
10574648 - Omega-3 polyunsaturated fatty acids and ventricular fibrillation: the possible involvem...
11495468 - The effect of ethoxyquin on the quality of ground poultry mortality carcasses preserved...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of pharmaceutical sciences     Volume:  92     ISSN:  0022-3549     ISO Abbreviation:  J Pharm Sci     Publication Date:  2003 Nov 
Date Detail:
Created Date:  2003-11-06     Completed Date:  2004-06-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985195R     Medline TA:  J Pharm Sci     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2341-4     Citation Subset:  IM    
Copyright Information:
Copyright 2003 Wiley-Liss, Inc. and the American Pharmacists Association J Pharm Sci 92:2341-2344, 2003
Affiliation:
Department of Biomedical Engineering, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Chromatography, Gas
Decanoic Acids / chemistry*
Drug Compounding
Fluorescein / chemistry*
Lauric Acids / chemistry*
Microspheres
Powders
Reference Standards
Surface-Active Agents / chemistry*
Chemical
Reg. No./Substance:
0/Decanoic Acids; 0/Lauric Acids; 0/Powders; 0/Surface-Active Agents; 2321-07-5/Fluorescein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mobility of water in human stratum corneum.
Next Document:  Dermatan sulfate exerts an enhanced growth factor response on skeletal muscle satellite cell prolife...