| Preparation and characterization of tegafur magnetic thermosensitive liposomes. | |
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MedLine Citation:
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PMID: 19630695 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The purpose was to study the preparation and properties of tegafur magnetic thermosensitive liposomes. The method was to employ an improved chemical coprecipitation method for preparing nano-magnetic particles and a reverse-phase evaporation and ultrasonic method for preparing tegafur magnetic thermosensitive liposomes. The results showed that tegafur magnetic thermosensitive liposomes were prepared successfully. They had comparatively strong magnetism and superparamagnetism, and their temperature showed a linear positive correlation with dosages and the field strength under a current value. The conclusion was that tegafur magnetic thermosensitive liposomes with comparatively small particle size, superparamagnetism and comparatively strong magnetism were prepared successfully. |
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Authors:
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Zhaowu Zeng; Xiaoli Wang; Yangde Zhang; Xingyan Liu; Weihua Zhou; Nianfeng Li |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Pharmaceutical development and technology Volume: 14 ISSN: 1097-9867 ISO Abbreviation: Pharm Dev Technol Publication Date: 2009 |
Date Detail:
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Created Date: 2009-07-27 Completed Date: 2009-12-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9610932 Medline TA: Pharm Dev Technol Country: England |
Other Details:
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Languages: eng Pagination: 350-7 Citation Subset: IM |
Affiliation:
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National Hepatobiliary & Enteric Surgery Research Center, Ministry of Health, Central South University, National Key Laboratory of Nanobiological Technology, Institute of Biomedical Engineering of Central South University, Changsha, Hunan, P.R. China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Antimetabolites, Antineoplastic
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administration & dosage,
chemistry* Chemical Precipitation Chemistry, Pharmaceutical / methods Liposomes Magnetics* Particle Size Tegafur / administration & dosage, chemistry* Temperature |
| Chemical | |
Reg. No./Substance:
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0/Antimetabolites, Antineoplastic; 0/Liposomes; 17902-23-7/Tegafur |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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