Document Detail


Preparation of Highly Functionalised Benzofurans from ortho-Hydroxyphenones and Dichloroethylene: Applications and Mechanistic Investigations.
MedLine Citation:
PMID:  23335128     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Highly functionalised benzofurans have been prepared from ortho-hydroxyphenones and 1,1-dichloroethylene. The key intermediate, a chloromethylene furan, smoothly rearranged into the corresponding benzofuran carbaldehyde under acidic conditions. Some mechanistic investigations have been performed and several biologically active benzofurans have been synthesised.
Authors:
Florian Schevenels; Bernard Tinant; Jean-Paul Declercq; István E Markó
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2013-1-18
Journal Detail:
Title:  Chemistry (Weinheim an der Bergstrasse, Germany)     Volume:  -     ISSN:  1521-3765     ISO Abbreviation:  Chemistry     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2013-1-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9513783     Medline TA:  Chemistry     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Affiliation:
Laboratory of Organic and Medicinal Chemistry, Université catholique de Louvain, Place Louis Pasteur 1 bte L4.01.02, 1348 Louvain-la-Neuve (Belgium), Fax: (+32) 10-472788.
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