Document Detail


Preparation of a 211At-IgG conjugate which is stable in vivo.
MedLine Citation:
PMID:  6526518     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The short lived (t 1/2 7.2 h) alpha-particle emitting halogen 211At has been attached to an antibody by using an acylation reaction to conjugate para-[211At]astato-benzoic acid with rabbit IgG. The conjugate, which is stable in vivo, contains at least 30% of the initial activity of 211At.
Authors:
A Harrison; L Royle
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The International journal of applied radiation and isotopes     Volume:  35     ISSN:  0020-708X     ISO Abbreviation:  Int J Appl Radiat Isot     Publication Date:  1984 Nov 
Date Detail:
Created Date:  1985-03-25     Completed Date:  1985-03-25     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0374715     Medline TA:  Int J Appl Radiat Isot     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1005-8     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Astatine*
Drug Stability
Immunoglobulin G*
Isotope Labeling / methods
Male
Mice
Mice, Inbred CBA
Chemical
Reg. No./Substance:
0/Immunoglobulin G; 7440-68-8/Astatine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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