| Preoperative staging of colorectal cancer: CT vs. integrated FDG PET/CT. | |
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MedLine Citation:
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PMID: 17610107 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Accurate preoperative staging is essential in determining the optimal therapeutic planning for individual patients. The computed tomography (CT) in the preoperative staging of colorectal cancer, even if controversial, may be useful for planning surgery and/or neoadjuvant therapy, particularly when local tumor extension into adjacent organs or distant metastases are detected. There have been significant changes in the CT technology with the advent of multi-detector row CT (MDCT) scanner. Advances in CT technology have raised interest in the potential role of CT for detection and staging of colorectal cancer. In recent studies, MDCT with MPR images has shown promising accuracy in the evaluation of local extent and nodal involvement of colorectal cancer. Combined PET/CT images have significant advantages over either alone because it provides both functional and anatomical data. Therefore, it is natural to expect that PET/CT would improve the accuracy of preoperative staging of colorectal cancer. The most significant additional information provided by PET/CT relates to the accurate detection of distant metastases. For the evaluation of patients with colorectal cancer, CT has relative advantages over PET/CT in regard to the depth of tumor invasion through the wall, extramural extension, and regional lymph node metastases. PET/CT should be performed on selected patients with suggestive but inconclusive metastatic lesions with CT. In addition, PET/CT with dedicated CT protocols, such as contrast-enhanced PET/CT and PET/CT colonography, may replace the diagnostic CT for the preoperative staging of colorectal cancer. |
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Authors:
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Sang Soo Shin; Yong Yeon Jeong; Jung Jun Min; Hyeong Rok Kim; Tae Woong Chung; Heoung Keun Kang |
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Publication Detail:
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Type: Comparative Study; Journal Article; Review |
Journal Detail:
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Title: Abdominal imaging Volume: 33 ISSN: 1432-0509 ISO Abbreviation: Abdom Imaging Publication Date: 2008 May-Jun |
Date Detail:
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Created Date: 2008-04-16 Completed Date: 2008-06-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9303672 Medline TA: Abdom Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 270-7 Citation Subset: IM |
Affiliation:
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Department of Diagnostic Radiology, Chonnam National University Medical School, #8 Hack-dong, Dong-gu, Gwangju, 501-757, South Korea. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Colorectal Neoplasms
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pathology*,
radiography,
radionuclide imaging,
surgery Fluorodeoxyglucose F18 / diagnostic use Humans Lymphatic Metastasis Neoplasm Metastasis Neoplasm Staging / methods* Preoperative Care* Prognosis Radiopharmaceuticals / diagnostic use Sensitivity and Specificity Tomography, Emission-Computed / methods* Tomography, X-Ray Computed / methods* |
| Chemical | |
Reg. No./Substance:
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0/Radiopharmaceuticals; 63503-12-8/Fluorodeoxyglucose F18 |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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