| Preoperative single-slab 3D time-of-flight magnetic resonance angiography predicts development of new cerebral ischemic events after carotid endarterectomy. Clinical article. | |
| | |
MedLine Citation:
|
PMID: 19267537 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECT: Preoperative impairment of cerebral hemodynamics predicts the development of new cerebral ischemic events after carotid endarterectomy (CEA), including neurological deficits and cerebral ischemic lesions on diffusion weighted MR imaging. Furthermore, the signal intensity of the middle cerebral artery (MCA) on single-slab 3D time-of-flight MR angiography (MRA) can assess hemodynamic impairment in the cerebral hemisphere. The purpose of the present study was to determine whether, on preoperative MR angiography, the signal intensity of the MCA can be used to identify patients at risk for development of cerebral ischemic events after CEA. METHODS: The signal intensity of the MCA ipsilateral to CEA on preoperative MR angiography was graded according to the ability to visualize the MCA in 106 patients with unilateral internal carotid artery stenosis (>or=70%). Diffusion weighted MR imaging was performed within 3 days of and 24 hours after surgery. The presence or absence of new postoperative neurological deficits was also evaluated. RESULTS: Cerebral ischemic events after CEA were observed in 16 patients. Reduced signal intensity of the MCA on preoperative MR angiography was the only significant independent predictor of postoperative cerebral ischemic events. When the reduced MCA signal intensity on preoperative MR angiography was defined as an impairment in cerebral hemodynamics, MR angiography grading resulted in an 88% sensitivity and 63% specificity, with a 30% positive- and a 97% negative-predictive value for the development of postoperative cerebral ischemic events. CONCLUSIONS: Signal intensity of the MCA on preoperative single-slab 3D time-of-flight MR angiography is useful for identifying patients at risk for cerebral ischemic events after CEA. |
| | |
Authors:
|
Taro Suzuki; Kuniaki Ogasawara; Ryonoshin Hirooka; Makoto Sasaki; Masakazu Kobayashi; Daiya Ishigaki; Shunro Fujiwara; Kenji Yoshida; Yasunari Otawara; Akira Ogawa |
Related Documents
:
|
17179367 - Reproducibility of postprocessing of quantitative ct perfusion maps. 19850897 - Neuroimaging demonstration of evolving small vessel ischemic injury in cerebral amyloid... 10146367 - Magnetic resonance imaging and p300 (event-related auditory evoked potentials) in the a... 670467 - Steroids and apparent cerebral atrophy on computed tomography scans. 18058647 - A case of intracranial hypoglossal neurinoma without hypoglossal nerve palsy: operative... 7891527 - Cerebral white matter in the centrum semiovale exhibits a larger n-acetyl signal than d... |
Publication Detail:
|
Type: Clinical Trial; Journal Article |
Journal Detail:
|
Title: Journal of neurosurgery Volume: 111 ISSN: 0022-3085 ISO Abbreviation: J. Neurosurg. Publication Date: 2009 Jul |
Date Detail:
|
Created Date: 2009-07-02 Completed Date: 2009-08-20 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0253357 Medline TA: J Neurosurg Country: United States |
Other Details:
|
Languages: eng Pagination: 141-6 Citation Subset: AIM; IM |
Affiliation:
|
Department of Neurosurgery, Advanced Medical Center, Iwate Medical University, Morioka, Japan. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Aged, 80 and over Brain Ischemia / epidemiology, pathology* Carotid Stenosis / epidemiology, pathology*, surgery* Diffusion Magnetic Resonance Imaging Endarterectomy, Carotid* Female Humans Magnetic Resonance Angiography / methods* Male Middle Aged Postoperative Complications / epidemiology, pathology* Predictive Value of Tests Preoperative Care Risk Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Multiinstitutional validation of the University of California at San Francisco Low-Grade Glioma Prog...
Next Document: Anatomical features of the cisternal segment of the oculomotor nerve: neurovascular relationships an...