Document Detail

Preoperative radiotherapy without femoral shielding for prevention of heterotopic ossification in hydroxyapatite-coated hip prostheses.
MedLine Citation:
PMID:  11409557     Owner:  NLM     Status:  MEDLINE    
Twenty-seven consecutive patients at high risk of developing heterotopic ossifications (HO) after implantation of a hydroxyapatite (HA)-coated hip prosthesis were irradiated with a single dose of 7 Gy, at least 4 h before the operation. The femoral stem was not shielded during radiotherapy (RT). After a median follow-up of 14.8 months, no clinically significant HO could be found, while 12 (52%) patients in this high-risk population had only minor HO (grade I). No reoperation was needed, and no evidence of prosthesis migration was observed. We conclude that single-dose, preoperative RT for HA-coated hip prosthesis can effectively inhibit HO. Not blocking the femoral stem does not result in prosthesis migration.
D Taussky; M Cserhati; R Pescia
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of orthopaedic and trauma surgery     Volume:  121     ISSN:  0936-8051     ISO Abbreviation:  Arch Orthop Trauma Surg     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-06-18     Completed Date:  2001-10-25     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9011043     Medline TA:  Arch Orthop Trauma Surg     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  271-3     Citation Subset:  IM    
Department of Radiotherapy, Triemli Hospital, Zürich, Switzerland.
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MeSH Terms
Aged, 80 and over
Arthroplasty, Replacement, Hip / adverse effects*
Coated Materials, Biocompatible
Hip Prosthesis
Middle Aged
Ossification, Heterotopic / prevention & control*,  radiotherapy*
Preoperative Care
Prosthesis Design
Radiotherapy Dosage
Reg. No./Substance:
0/Coated Materials, Biocompatible; 1306-06-5/Durapatite

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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