Document Detail

Preoperative location of the pituitary bright spot in patients with pituitary macroadenomas.
MedLine Citation:
PMID:  11950639     Owner:  NLM     Status:  MEDLINE    
BACKGROUND AND PURPOSE: The purpose of this study was to determine the location of the pituitary bright spot in patients with pituitary macroadenomas before surgery. METHODS: A total of 54 patients with pituitary macroadenomas were retrospectively included in this study. Nonenhanced spin-echo T1-weighted MR images were reviewed to identify the location of the high-intensity-signal posterior pituitary lobe that indicates antidiuretic hormone (ADH) storage. Images were acquired with a 1.5-T machine by using 3-mm-thick contiguous sections in two or three orthogonal planes and a 300 x 512 matrix. RESULTS: The bright spot corresponding to ADH storage was identified in 44 (81%) patients. Two groups of patients were defined by the height of the macroadenoma: Group A patients (n = 27) had pituitary macroadenomas less than 20 mm in height, and group B (n = 27) had macroadenomas 20 mm or larger. In group A, the bright spot was identified in 25 patients (93%); it was located in the sella in 24 of these cases (96%). In group B, the bright spot was identified in 19 patients (70%); it was in an ectopic location in 14 of these cases (74%). CONCLUSION: MR imaging can be used to depict the pituitary bright spot in most patients with pituitary macroadenomas before surgery. The bright spot is usually identified at its expected location within the sella in patients with pituitary macroadenomas less than 20 mm in height, whereas an ectopic location is common when pituitary macroadenomas are larger more than 20 mm.
Fabrice Bonneville; Yvan Narboux; Françoise Cattin; Emmanuel Rodière; Guy Jacquet; Jean-François Bonneville
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  AJNR. American journal of neuroradiology     Volume:  23     ISSN:  0195-6108     ISO Abbreviation:  AJNR Am J Neuroradiol     Publication Date:  2002 Apr 
Date Detail:
Created Date:  2002-04-12     Completed Date:  2002-05-09     Revised Date:  2008-02-14    
Medline Journal Info:
Nlm Unique ID:  8003708     Medline TA:  AJNR Am J Neuroradiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  528-32     Citation Subset:  IM    
Department of Neuroradiology, Hôpital Jean Minjoz, France.
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MeSH Terms
Adenoma / diagnosis*,  surgery
Aged, 80 and over
Magnetic Resonance Imaging*
Middle Aged
Pituitary Gland, Posterior / pathology*,  secretion
Pituitary Neoplasms / diagnosis*,  surgery
Retrospective Studies
Vasopressins / secretion
Reg. No./Substance:

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