Document Detail


Preoperative localization of parathyroid lesion: diagnostic usefulness of color doppler ultrasonography.
MedLine Citation:
PMID:  22328952     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
INTRODUCTION: Recently, minimally invasive parathyroidectomy (MIP) has been developed and is gaining popularity among surgeons. For this reason, preoperative localization is playing an important role to detect the precise location of the affected gland and to increase the success rate.
MATERIAL AND METHODS: From June 2007 to June 2011, 56 consecutive patients (11 men and 45 women) with primary or secondary hyperparathyroidism in our center underwent Gray scale, color Doppler and 99m-Tc MIBI scan prior to operative management of parathyroid lesions.
RESULTS: The sensitivity, specificity and accuracy of US and MIBI scan for pHPT was 88%, 94%, 91% and 70%, 100% and 85% respectively. In patients with sHPT, the sensitivity, specificity and accuracy of US and MIBI scan was 54%, 93%, 76% and 25%, 100% and 72.9% respectively. The overall sensitivity of combined US and MIBI scan in pHPT and sHPT was 97% and 45% respectively. The overall sensitivity, specificity and accuracy of CDUS in diagnosis of parathyroid lesions in pHPT and sHPT is 97%, 100%, 98.6% and 62%, 100% and 83% respectively.
CONCLUSION: The overall sensitivity and specificity of US and MIBI in preoperative localization of parathyroid adenoma in sHPT is lower than pHPT and performing CDUS can increases the overall sensitivity and specificity of imaging methods in accurate localization of parathyroid lesion.
Authors:
Afshin Mohammadi; Farzad Moloudi; Mohammad Ghasemi-Rad
Publication Detail:
Type:  Journal Article     Date:  2012-01-15
Journal Detail:
Title:  International journal of clinical and experimental medicine     Volume:  5     ISSN:  1940-5901     ISO Abbreviation:  Int J Clin Exp Med     Publication Date:  2012  
Date Detail:
Created Date:  2012-02-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101471010     Medline TA:  Int J Clin Exp Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  80-6     Citation Subset:  -    
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