Document Detail


Preoperative differentiation between carcinoma of the pancreas and chronic pancreatitis: the contribution of cytology.
MedLine Citation:
PMID:  7117208     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a prospective study of 54 consecutive patients where carcinoma of the pancreas was suspected, a simple protocol was employed. Each patient had duodenoscopy and pancreatic juice cytology. Those patients with jaundice had cholangiography by percutaneous or endoscopic retrograde technique. Patients who were not jaundiced had endoscopic retrograde cholangiopancreatography. Malignancy, confirmed by histology, was diagnosed in 25 patients. Patients diagnosed to have benign disease have been followed for two years and in none has the diagnosis changed to malignancy. Twenty-one of those with carcinoma were correctly diagnosed on the basis of cholangiograms or pancreatograms but there were three false-positive diagnoses of malignancy. Cytology identified 15 of the 25 with carcinoma; there were no false positive diagnoses. Pancreatic cytology is highly specific for the diagnosis of carcinoma and should be used early. In patients with negative cytology, an acceptable level of accuracy can be achieved by a combination of endoscopy and radiology.
Authors:
D R Hunt; L H Blumgart
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Endoscopy     Volume:  14     ISSN:  0013-726X     ISO Abbreviation:  Endoscopy     Publication Date:  1982 Sep 
Date Detail:
Created Date:  1982-12-03     Completed Date:  1982-12-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0215166     Medline TA:  Endoscopy     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  171-3     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Carcinoma / diagnosis*
Cholangiopancreatography, Endoscopic Retrograde
Chronic Disease
Diagnosis, Differential
Duodenoscopy
False Positive Reactions
Humans
Pancreatic Juice / cytology*
Pancreatic Neoplasms / diagnosis*
Pancreatitis / diagnosis*
Preoperative Care
Prospective Studies

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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