| Preoperative combined 18-fluorodeoxyglucose positron emission tomography and computed tomography imaging in head and neck cancer: does it really improve initial N staging? | |
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MedLine Citation:
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PMID: 20735322 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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CONCLUSION: In our experience PET-CT cannot yet reliably predict the need for surgical neck dissection in patients with N0 neck. According to the results of PET-CT the neck dissection should be extended towards unusual lymph node areas. OBJECTIVE: To analyze the value of PET-CT for the initial N staging, comparing PET-CT data with histopathological results of the modified radical neck dissection. METHODS: Fifty patients with previously untreated head and neck squamous cell carcinoma were eligible for inclusion in this study. Modified radical unilateral or bilateral neck dissection was performed in all patients. PET-CT findings and histological findings were compared to determine their diagnostic sensitivity, specificity, accuracy, positive predictive value, and negative predictive value. RESULTS: In all, 105 levels had pathologically diagnosed metastases: PET-CT was positive in 87 levels and negative in 18 levels. Also, 399 levels had negative postoperative histology findings: PET-CT was positive in 24 levels and negative in 375 levels. The false-positive over-staged and the false-negative under-staged rates were 27% and 12%, respectively. |
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Authors:
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Celine Richard; Nathalie Prevot; Andrei P Timoshenko; Jean-Marc Dumollard; Francis Dubois; Christian Martin; Jean-Michel Prades |
Publication Detail:
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Type: Journal Article Date: 2010-08-25 |
Journal Detail:
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Title: Acta oto-laryngologica Volume: 130 ISSN: 1651-2251 ISO Abbreviation: Acta Otolaryngol. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370354 Medline TA: Acta Otolaryngol Country: England |
Other Details:
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Languages: eng Pagination: 1421-4 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology - Head and Neck Surgery, North Hospital, University Hospital Centre, Saint-Etienne, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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