Document Detail


Preoperative colonoscopy for patients with gastric adenocarcinoma.
MedLine Citation:
PMID:  19686412     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND AND AIM: In patients with gastric adenocarcinoma (GA), the most common double primary cancer is colorectal cancer. The aim of the present study was to evaluate the necessity of preoperative colonoscopy in patients with GA who have no symptoms of colorectal disease or any past/family history of colorectal cancer. MATERIALS: Colonoscopy was carried out in 205 patients before gastric surgery for treatment of GA. The prevalence of colorectal neoplasms (CRN, adenoma and adenocarcinoma) was evaluated according to age, sex, body mass index (BMI) and stage, location and differentiation of GA. RESULTS: The median age and BMI were 59 years (range 32-81) and 22.9 (range 17.0-42.3), respectively. There were 135 male patients (65.9%). Synchronous adenoma and adenocarcinoma were detected in 68 (33.2%) and four (2.0%) patients, respectively. Univariate analysis showed that patients 50 years and older, male or with multiple GA had a significantly higher incidence of CRN (P = 0.005, 0.019, and 0.023, respectively). All of the GA patients with synchronous colorectal adenocarcinoma were older than 50 years. The stage, location and differentiation of GA and BMI did not show a significant difference in the incidence of CRN. Multivariate analysis showed that age (50 years and older) was the only risk factor of CRN in GA patients (odds ratio 2.470; 95% confidence interval 1.058-5.767). CONCLUSION: Preoperative colonoscopy for screening of CRN should be considered in GA patients > or = 50 years because of a relatively high prevalence of CRN and the possibility of synchronous CRC.
Authors:
Hyung Ook Kim; Sang Il Hwang; Chang Hak Yoo; Hungdai Kim
Publication Detail:
Type:  Evaluation Studies; Journal Article     Date:  2009-08-03
Journal Detail:
Title:  Journal of gastroenterology and hepatology     Volume:  24     ISSN:  1440-1746     ISO Abbreviation:  J. Gastroenterol. Hepatol.     Publication Date:  2009 Nov 
Date Detail:
Created Date:  2010-02-08     Completed Date:  2010-04-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8607909     Medline TA:  J Gastroenterol Hepatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  1740-4     Citation Subset:  IM    
Affiliation:
Departments of Surgery, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.
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MeSH Terms
Descriptor/Qualifier:
Adenocarcinoma / epidemiology,  pathology*,  surgery
Adenoma / epidemiology,  pathology*
Adult
Age Factors
Aged
Aged, 80 and over
Colonoscopy*
Colorectal Neoplasms / epidemiology,  pathology*
Databases as Topic
Female
Gastrectomy*
Humans
Incidence
Logistic Models
Male
Mass Screening / methods*
Middle Aged
Neoplasm Staging
Neoplasms, Second Primary*
Odds Ratio
Predictive Value of Tests
Preoperative Care
Prevalence
Risk Assessment
Risk Factors
Stomach Neoplasms / epidemiology,  pathology*,  surgery

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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