Document Detail


Preoperative blastformation rate in gastrointestinal cancer patients.
MedLine Citation:
PMID:  145162     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The rate of blastformation of peripheral blood lymphocytes in response to stimulation by phytohemagglutinin (PHA) was assessed preoperatively in 393 patients with gastrointestinal cancer. The series consisted of 291 cases of gastric cancer and 102 cases of colon cancer, all patients being under 70 years of age. The blastformation rate was related to the stage of cancer ground at operation. Preoperative blastformation rates for both colon cancer and gastric cancer decreased as the cancer progressed. With Stage I gastric cancer 81.4% of those that underwent curative resection had preoperative blastformation rates greater than 40%. However, the number of those with blastformation rates over 40% decreased markedly in the curative cases of gastric cancer Stage II to stage IV. Eighty three percent of cases that underwent curative resection with colon cancer, including advanced cancer, had preoperative blastformation rates of over 40%. These results indicated that the correlation of the preoperative blastformation rate with success of curative resection better for colon cancer than for gastric cancer.
Authors:
H Miwa; K Orita
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta medica Okayama     Volume:  31     ISSN:  0386-300X     ISO Abbreviation:  Acta Med. Okayama     Publication Date:  1977 Aug 
Date Detail:
Created Date:  1978-01-27     Completed Date:  1978-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0417611     Medline TA:  Acta Med Okayama     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  257-62     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Aged
Colonic Neoplasms / immunology,  surgery*
Humans
Lymphocyte Activation*
Stomach Neoplasms / immunology,  surgery*

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