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Preoperative Anemia Does Not Increase the Risks of Early Surgical Revascularization After Myocardial Infarction.
MedLine Citation:
PMID:  22939451     Owner:  NLM     Status:  Publisher    
BACKGROUND: Recent clinical studies suggest preoperative anemia may increase mortality and morbidity after cardiac surgery. Anemic patients are potentially even more vulnerable in the setting of a recent myocardial infarction (MI). The objective of this study was to investigate the impact of preoperative anemia on short-term outcomes after coronary bypass surgery in patients with a recent MI. METHODS: We conducted a retrospective cohort study of 655 patients who underwent an isolated coronary bypass procedure within 21 days of MI, 432 of whom were anemic preoperatively, defined as a hemoglobin less than 13 g/dL for men and less than 12 g/dL for women. The primary outcomes were in-hospital mortality and major adverse events (MAE), which included MI, stroke, and renal failure requiring dialysis. RESULTS: Before risk adjustment, in-hospital mortality and the incidence of MAE were significantly higher in patients with anemia versus no anemia (mortality, 5.1% versus 1.4%, p = 0.02; MAE, 8.6% versus 3.1%, p = 0.009). After risk adjustment, the association between preoperative anemia and mortality or MAE became insignificant (mortality odds ratio 2.34, 95% confidence interval: 0.56 to 9.87, p = 0.25; MAE odds ratio 1.13, 95% confidence interval: 0.46 to 2.79, p = 0.78). Preoperative hemoglobin, treated as a continuous variable, yielded similar results. CONCLUSIONS: Preoperative anemia does not directly increase risks of surgical revascularization performed within 21 days of MI.
Li Zhang; Brett Hiebert; Ryan Zarychanski; Rakesh C Arora;
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-29
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  -     ISSN:  1552-6259     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-9-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.
Cardiac Sciences Program, St. Boniface Hospital/I. H. Asper Clinical Research Institute, University of Manitoba, Winnipeg, Manitoba, Canada.
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