| Preoperative Anemia Does Not Increase the Risks of Early Surgical Revascularization After Myocardial Infarction. | |
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MedLine Citation:
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PMID: 22939451 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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BACKGROUND: Recent clinical studies suggest preoperative anemia may increase mortality and morbidity after cardiac surgery. Anemic patients are potentially even more vulnerable in the setting of a recent myocardial infarction (MI). The objective of this study was to investigate the impact of preoperative anemia on short-term outcomes after coronary bypass surgery in patients with a recent MI. METHODS: We conducted a retrospective cohort study of 655 patients who underwent an isolated coronary bypass procedure within 21 days of MI, 432 of whom were anemic preoperatively, defined as a hemoglobin less than 13 g/dL for men and less than 12 g/dL for women. The primary outcomes were in-hospital mortality and major adverse events (MAE), which included MI, stroke, and renal failure requiring dialysis. RESULTS: Before risk adjustment, in-hospital mortality and the incidence of MAE were significantly higher in patients with anemia versus no anemia (mortality, 5.1% versus 1.4%, p = 0.02; MAE, 8.6% versus 3.1%, p = 0.009). After risk adjustment, the association between preoperative anemia and mortality or MAE became insignificant (mortality odds ratio 2.34, 95% confidence interval: 0.56 to 9.87, p = 0.25; MAE odds ratio 1.13, 95% confidence interval: 0.46 to 2.79, p = 0.78). Preoperative hemoglobin, treated as a continuous variable, yielded similar results. CONCLUSIONS: Preoperative anemia does not directly increase risks of surgical revascularization performed within 21 days of MI. |
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Authors:
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Li Zhang; Brett Hiebert; Ryan Zarychanski; Rakesh C Arora; |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-29 |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: - ISSN: 1552-6259 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-9-3 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved. |
Affiliation:
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Cardiac Sciences Program, St. Boniface Hospital/I. H. Asper Clinical Research Institute, University of Manitoba, Winnipeg, Manitoba, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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