| Prenylated xanthones from Garcinia xanthochymus. | |
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MedLine Citation:
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PMID: 14600386 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A new prenylated xanthone, 1,3,5,6-tetrahydroxy-4,7,8-tri(3-methyl-2-butenyl)xanthone (1), was isolated from the wood of Garcinia xanthochymus together with a known xanthone, garciniaxanthone E (2). Their structures were determined by spectroscopic analysis. Compounds 1 (3 microM) and 2 (10 microM) elicited marked enhancement of nerve growth factor-mediated neurite outgrowth in PC12D cells. |
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Authors:
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Wisinee Chanmahasathien; Yushan Li; Masayuki Satake; Yasukatsu Oshima; Masami Ishibashi; Nijsiri Ruangrungsi; Yasushi Ohizumi |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Chemical & pharmaceutical bulletin Volume: 51 ISSN: 0009-2363 ISO Abbreviation: Chem. Pharm. Bull. Publication Date: 2003 Nov |
Date Detail:
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Created Date: 2003-11-05 Completed Date: 2004-06-25 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0377775 Medline TA: Chem Pharm Bull (Tokyo) Country: Japan |
Other Details:
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Languages: eng Pagination: 1332-4 Citation Subset: IM |
Affiliation:
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Graduate School of Pharmaceutical Sciences, Tohoku University, Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Drug Synergism Garcinia / chemistry* Magnetic Resonance Spectroscopy Nerve Growth Factors / pharmacology Neurites / drug effects PC12 Cells Plant Extracts / chemistry Protein Prenylation Rats Spectrometry, Mass, Electrospray Ionization Spectrophotometry, Infrared Spectrophotometry, Ultraviolet Wood Xanthones / chemistry*, isolation & purification, pharmacology |
| Chemical | |
Reg. No./Substance:
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0/Nerve Growth Factors; 0/Plant Extracts; 0/Xanthones |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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