Document Detail

Prenatal syphilis infection is a possible cause of preterm delivery among immigrant women from eastern Europe.
MedLine Citation:
PMID:  17098768     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: to evaluate the prevalence of maternal syphilis at delivery and neonatal syphilis infection in an Italian urban area, in connection with the increased flow of immigration.
STUDY DESIGN: A prospective surveillance study was carried out in Bologna, Italy, from November 2000 to March 2006. All pregnant women were screened for syphilis at delivery. Infants born to seropositive mothers were enrolled in a prospective follow-up.
RESULTS: During the study period 19,205 women gave birth to 19,548 infants. A total of 85 women were seropositive for syphilis at delivery. The overall syphilis seroprevalence in pregnant women was 0.44%, but it was 4.3% in women from eastern Europe and 5.8% in women from Central-South America. Ten women were first found positive at delivery, as they did not receive any prenatal care. Nine of these were from eastern Europe. All their infants were asymptomatic, but six had both reactive immunoglobulin (Ig)M western blot and rapid plasma reagin tests and were considered prenatally infected. Three of six were preterm (gestational age <37 weeks).
CONCLUSIONS: In Italy, congenital syphilis infection is strictly related to immigration from eastern Europe. Although it is asymptomatic, it could cause premature delivery. Therefore, it is necessary to perform serological tests during the third trimester in mothers coming from endemic areas to adequately treat syphilis in pregnancy and prevent congenital infection. If the mother's test results are not available at delivery, it is necessary to investigate the newborn, especially if it is born prematurely.
E Tridapalli; M G Capretti; V Sambri; A Marangoni; A Moroni; A D'Antuono; M L Bacchi; G Faldella
Related Documents :
2550518 - Prospective study of community-acquired rotavirus infection.
9264888 - Does routine gowning reduce nosocomial infection and mortality rates in a neonatal nurs...
20569168 - Innate immunity in human newborn infants: prematurity means more than immaturity.
12200608 - Severe coxsackie virus b infection in preterm newborns treated with pleconaril.
9325878 - Stool patterns of infants diagnosed with necrotizing enterocolitis.
24246598 - Methylxanthine use for apnea of prematurity among an international cohort of neonatolog...
Publication Detail:
Type:  Journal Article     Date:  2006-11-10
Journal Detail:
Title:  Sexually transmitted infections     Volume:  83     ISSN:  1368-4973     ISO Abbreviation:  Sex Transm Infect     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-16     Completed Date:  2007-05-25     Revised Date:  2013-06-07    
Medline Journal Info:
Nlm Unique ID:  9805554     Medline TA:  Sex Transm Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  102-5     Citation Subset:  IM    
Department of Preventive Paediatrics and Neonatology; St Orsola Malpighi General Hospital, University of Bologna, Bologna, Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Emigration and Immigration
Europe, Eastern
Follow-Up Studies
Maternal Age
Pregnancy Complications, Infectious / ethnology,  microbiology*
Premature Birth / ethnology,  microbiology*
Prospective Studies
Syphilis Serodiagnosis
Syphilis, Congenital / ethnology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The association between knowledge of HPV and feelings of stigma, shame and anxiety.
Next Document:  Fear of venepuncture as a barrier to testing for blood-borne infection and use of an oral fluid test...