Document Detail


Prenatal sonographic features of fetuses in trisomy 13 pregnancies. IV.
MedLine Citation:
PMID:  20466286     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Prenatal ultrasound is a powerful tool to detect structural abnormalities associated with the fetuses in trisomy 13 pregnancies. This article provides a comprehensive review of the prenatal sonographic markers of trisomy 13 in the first trimester, including fetal nuchal translucency thickness, fetal heart rate, fetal nasal bone, fetal tricuspid regurgitation, ductus venous flow, fetal crown-rump length, fetal trunk and head volume, fetal frontomaxillary facial angle, gestational sac volume and umbilical cord diameter, along with biochemical markers such as maternal serum free beta-human chorionic gonadotropin, maternal serum pregnancy-associated plasma protein-A, maternal serum placental growth factor, and the fetal and total cell-free DNA concentration in the maternal circulation.
Authors:
Chih-Ping Chen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Taiwanese journal of obstetrics & gynecology     Volume:  49     ISSN:  1875-6263     ISO Abbreviation:  Taiwan J Obstet Gynecol     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-05-14     Completed Date:  2010-08-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101213819     Medline TA:  Taiwan J Obstet Gynecol     Country:  China    
Other Details:
Languages:  eng     Pagination:  3-12     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Mackay Memorial Hospital, Taipei, Taiwan. cpc_mmh@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Aneuploidy
Cephalometry
Chorionic Gonadotropin, beta Subunit, Human / blood
Chromosomes, Human, Pair 13*
Crown-Rump Length
DNA / blood
Ductus Arteriosus / ultrasonography
Face / embryology,  ultrasonography
Facial Asymmetry / ultrasonography
Female
Heart Defects, Congenital / ultrasonography
Heart Rate, Fetal
Humans
Maternal Age
Maxilla / embryology,  ultrasonography
Nasal Bone / abnormalities,  embryology,  ultrasonography
Nuchal Translucency Measurement
Pregnancy
Pregnancy Proteins / blood
Pregnancy Trimester, First
Pregnancy-Associated Plasma Protein-A / analysis
Tricuspid Valve Insufficiency / ultrasonography
Trisomy / diagnosis*
Ultrasonography, Prenatal*
Umbilical Cord / ultrasonography
Chemical
Reg. No./Substance:
0/Chorionic Gonadotropin, beta Subunit, Human; 0/Pregnancy Proteins; 144589-93-5/placenta growth factor; 9007-49-2/DNA; EC 3.4.24.-/Pregnancy-Associated Plasma Protein-A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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