| Prenatal pharmacotherapy for fetal anomalies: a 2011 update. | |
| | |
MedLine Citation:
|
PMID: 21638296 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Fetal therapy can be defined as any prenatal treatment administered to the mother with the primary indication to improve perinatal or long-term outcomes for the fetus or newborn. This review provides an update of the pharmacological therapies that are solely directed at the fetus with anomalies and outlines a future transcriptomic approach. Fetal anomalies targeted with prenatal pharmacotherapy are a heterogeneous group of structural, endocrine, and metabolic conditions, including congenital cystic adenomatoid malformation (CCAM), congenital adrenal hyperplasia, congenital heart block, fetal tachyarrhythmias, inborn errors of metabolism, fetal thyroid disorders, and polyhydramnios. To date, the majority of pharmacotherapies for fetal anomalies have been evaluated only in retrospective, uncontrolled studies. The way forward will be with an evidence-based approach to prenatal pharmacological interventions. Copyright © 2011 John Wiley & Sons, Ltd. |
| | |
Authors:
|
Lisa Hui; Diana W Bianchi |
Related Documents
:
|
15675036 - The moral status of a human fetus: a response to lee. 17355376 - Abortion among young women and subsequent life outcomes. 6594246 - Clinical, immunologic, and genetic definitions of primary and secondary recurrent spont... 1986486 - Spontaneous abortion. 2734236 - A hypothesis on the increasing rates of ectopic pregnancy. 15675036 - The moral status of a human fetus: a response to lee. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-6-3 |
Journal Detail:
|
Title: Prenatal diagnosis Volume: - ISSN: 1097-0223 ISO Abbreviation: - Publication Date: 2011 Jun |
Date Detail:
|
Created Date: 2011-6-3 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8106540 Medline TA: Prenat Diagn Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 John Wiley & Sons, Ltd. |
Affiliation:
|
Mother Infant Research Institute, Tufts Medical Center, Boston, MA, USA; Division of Genetics, Department of Pediatrics, The Floating Hospital for Children at Tufts Medical Center, Boston, MA, USA; Discipline of Obstetrics, Gynaecology and Neonatology, University of Sydney, Sydney, NSW, Australia. LHui@tuftsmedicalcenter.org. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Brownian dynamics simulations on CPU and GPU with BD_BOX.
Next Document: The effect of L-arginine or L-citrulline supplementation on biochemical parameters and the vascular ...