Document Detail


Prenatal pattern emergence in early human facial development.
MedLine Citation:
PMID:  3422605     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This report addresses the emergence of proportional patterns in the early development of the human face. Fifty-nine human embryos and fetuses (7 through 26 weeks fertilization age) constituted a "normal" study sample. Midfacial cephalometric analyses were done on projected histologic sections cut frontally through the maxillary deciduous first molar tooth crowns. The midface was divided into three cephalometric zones. Data show that while each zone increases in absolute width, least change is seen in the central facial zone, with greatest change seen in the lateral-most facial zone. This pattern of proportional stability of the central facial zone becomes evident at 9 weeks gestation, at which time the changing embryonic optical axes have converged toward the midline to within several degrees of their position at birth. These data show that the central portion of the postnatal facial T-zone has a clearly recognizable prenatal antecedent as early as the ninth week in fetal life.
Authors:
A R Burdi; T J Lawton; J Grosslight
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Cleft palate journal     Volume:  25     ISSN:  0009-8701     ISO Abbreviation:  Cleft Palate J     Publication Date:  1988 Jan 
Date Detail:
Created Date:  1988-03-25     Completed Date:  1988-03-25     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0372737     Medline TA:  Cleft Palate J     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  8-15     Citation Subset:  D; IM    
Affiliation:
Department of Anatomy & Cell Biology, University of Michigan, Ann Arbor.
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MeSH Terms
Descriptor/Qualifier:
Cephalometry
Embryo, Mammalian
Embryonic and Fetal Development
Eye / embryology
Face / embryology*
Facial Bones / embryology
Female
Fetus
Gestational Age
Humans
Jaw / embryology
Male
Grant Support
ID/Acronym/Agency:
DE 03610/DE/NIDCR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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