Document Detail


Prenatal microcephaly: can we be more accurate?
MedLine Citation:
PMID:  19168823     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Consultation regarding isolated fetal microcephaly is especially difficult in a genetically heterogeneous population, as one of the factors associated with head circumference difference is ethnicity. The study presents four women referred to the neuro-fetal clinic for isolated fetal microcephaly. All fetuses had normal chromosomes, no structural abnormalities, or evidence of intrauterine infection or intoxication. Their head circumference measurements were 2 to 3 standard deviations below average for age on repeat ultrasound and fetal magnetic resonance imaging. Striking differences in chart placements were found between different professionals using different charts. In all children, measured head circumference after birth/termination was within normal limits. This study suggests that national charts should be built measuring fetal size adjusted for ethnicity and based on a genetically heterogeneous population. The charts should be customized between different professionals assessing prenatal and postnatal head circumference.
Authors:
Itai Berger
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of child neurology     Volume:  24     ISSN:  1708-8283     ISO Abbreviation:  J. Child Neurol.     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2009-01-26     Completed Date:  2009-09-30     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8606714     Medline TA:  J Child Neurol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  97-100     Citation Subset:  IM    
Affiliation:
Neuro-Fetal Clinic, Neuro-Pediatric Unit, Hadassah-Hebrew University Medical Center, Jerusalem, Israel. itberg@hadassah.org.il
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MeSH Terms
Descriptor/Qualifier:
Adult
Cephalometry / methods
Female
Fetus / pathology
Humans
Magnetic Resonance Imaging / methods*
Microcephaly / diagnosis*,  pathology
Pregnancy
Ultrasonography, Prenatal / methods*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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