Document Detail

Prenatal management of a congenital infantile fibrosarcoma: unexpected outcome.
MedLine Citation:
PMID:  21077153     Owner:  NLM     Status:  Publisher    
Objectives are to describe the contribution of magnetic resonance imaging (MRI) to prenatal diagnosis of congenital infantile fibrosarcoma, to discuss the treatment options, and to advise close monitoring of the pregnancy because of the risk of rupture of the tumor in utero.We report the case of a large leg tumor in a fetus at 36 weeks of gestation. The tumor's location and ultrasound characteristics and MRI enabled prenatal diagnosis of congenital fibrosarcoma and to establish its prognosis. After multidisciplinary discussion, it was decided the pregnancy should continue to 38 weeks, with surgery or neo-adjuvant chemotherapy scheduled after delivery. Unfortunately, the tumor unexpectedly burst in utero and the newborn died of the consequences of hemorrhagic shock, despite rapid amputation. Histological examination confirmed the nature of the tumor.The prognosis of congenital fibrosarcoma is good when there are no metastases, and treatment is now consensual. MRI is key to establishing a prenatal diagnosis. Rupture of the tumor can result in fatal hemorrhaging and the pregnancy should be monitored closely before scheduled delivery. Copyright © 2010 ISUOG. Published by John Wiley & Sons, Ltd.
Coralie Dumont; Mathilde Monforte; Anaïg Flandrin; Alain Couture; Renaud Tichit; Pierre Boulot
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2010-11-12
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  -     ISSN:  1469-0705     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Obstetrics and Gynaecology, CHU Arnaud de Villeneuve, Montpellier, France.
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