| Prenatal genetic screening in the Ashkenazi Jewish population. | |
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MedLine Citation:
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PMID: 11499058 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The Ashkenazi Jewish community is a unique and ideal population in which to provide multiple disease screening because detection rates are high (> 95%) by testing a limited number of mutations. The residual risk that remains is very low. In addition, the lessons learned from carrier screening in this community indicate that only through genetic counseling and education can screening in the general population gain wide acceptance and provide maximum benefit. |
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Authors:
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R E Zinberg; R Kornreich; L Edelmann; R J Desnick |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Clinics in perinatology Volume: 28 ISSN: 0095-5108 ISO Abbreviation: Clin Perinatol Publication Date: 2001 Jun |
Date Detail:
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Created Date: 2001-08-13 Completed Date: 2002-02-07 Revised Date: 2009-11-19 |
Medline Journal Info:
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Nlm Unique ID: 7501306 Medline TA: Clin Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 367-82 Citation Subset: IM |
Affiliation:
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Department of Human Genetics and Center for Jewish Genetic Diseases, Mount Sinai School of Medicine, New York University, New York, New York, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Counseling Genetic Diseases, Inborn / diagnosis*, ethnology* Genetic Predisposition to Disease Genetic Testing / methods* Heterozygote Detection Humans Jews / genetics* Mutation Prenatal Diagnosis* Risk Factors |
| Grant Support | |
ID/Acronym/Agency:
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5 M01 RR00071/RR/NCRR NIH HHS; 5 P30 HD28822/HD/NICHD NIH HHS; 5 R37 DK34045/DK/NIDDK NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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