Document Detail


Prenatal genetic screening in the Ashkenazi Jewish population.
MedLine Citation:
PMID:  11499058     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The Ashkenazi Jewish community is a unique and ideal population in which to provide multiple disease screening because detection rates are high (> 95%) by testing a limited number of mutations. The residual risk that remains is very low. In addition, the lessons learned from carrier screening in this community indicate that only through genetic counseling and education can screening in the general population gain wide acceptance and provide maximum benefit.
Authors:
R E Zinberg; R Kornreich; L Edelmann; R J Desnick
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.; Review    
Journal Detail:
Title:  Clinics in perinatology     Volume:  28     ISSN:  0095-5108     ISO Abbreviation:  Clin Perinatol     Publication Date:  2001 Jun 
Date Detail:
Created Date:  2001-08-13     Completed Date:  2002-02-07     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  367-82     Citation Subset:  IM    
Affiliation:
Department of Human Genetics and Center for Jewish Genetic Diseases, Mount Sinai School of Medicine, New York University, New York, New York, USA.
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MeSH Terms
Descriptor/Qualifier:
Counseling
Genetic Diseases, Inborn / diagnosis*,  ethnology*
Genetic Predisposition to Disease
Genetic Testing / methods*
Heterozygote Detection
Humans
Jews / genetics*
Mutation
Prenatal Diagnosis*
Risk Factors
Grant Support
ID/Acronym/Agency:
5 M01 RR00071/RR/NCRR NIH HHS; 5 P30 HD28822/HD/NICHD NIH HHS; 5 R37 DK34045/DK/NIDDK NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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