Document Detail


Prenatal findings in a monozygotic twin pregnancy with Costello syndrome.
MedLine Citation:
PMID:  12001198     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
This report describes the prenatal findings in monozygotic twins with Costello syndrome. At 16 weeks one twin had 9 mm of nuchal oedema: coarctation of the aorta was diagnosed after birth. At 22(5/7) weeks relative macrocephaly, mild pyelectasia and moderate polyhydramnios were noted in both twins. In the following 4 weeks the polyhydramnios increased significantly without visualisation of filling of the stomach. Between 27(5/7) and 30(2/7) weeks a total of 9 l amniotic fluid was drained and at 30(4/7) weeks prelabor premature rupture of membranes (PPROM) occurred followed by premature labor and delivery. The neonatal period was complicated by growth retardation, deglutition problems, hypotonia, cardiac and respiratory problems. Both twins died on Day 57 because of respiratory insufficiency.
Authors:
T Van den Bosch; D Van Schoubroeck; J P Fryns; G Naulaers; A M Inion; K Devriendt
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  22     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2002 May 
Date Detail:
Created Date:  2002-05-23     Completed Date:  2002-09-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  England    
Other Details:
Languages:  eng     Pagination:  415-7     Citation Subset:  IM    
Copyright Information:
Copyright 2002 John Wiley & Sons, Ltd.
Affiliation:
Department of Obstetrics and Gynaecology, A. Z. Heilig Hart, Tienen, Belgium. thierry.van_den_bosch@pi.be
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / pathology*
Adult
Diseases in Twins*
Fatal Outcome
Female
Fetal Diseases / pathology*
Humans
Polyhydramnios
Pregnancy
Prenatal Diagnosis*
Syndrome
Twins, Monozygotic*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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