Document Detail

Prenatal exposure to arecoline (areca nut alkaloid) and birth outcomes.
MedLine Citation:
PMID:  15846024     Owner:  NLM     Status:  MEDLINE    
The betel nut is commonly used as a drug by Asian populations. A high prevalence of adverse pregnancy outcomes has been reported in women who chewed betel quid during gestation. The hypothesis that chronic exposure of the fetus to arecoline (the principal alkaloid of the areca nut) is the cause was investigated in a clinical observational study on six newborns from Asian mothers who chewed betel nut during pregnancy.
O García-Algar; O Vall; F Alameda; C Puig; M Pellegrini; R Pacifici; S Pichini
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  90     ISSN:  1359-2998     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  2005 May 
Date Detail:
Created Date:  2005-04-22     Completed Date:  2005-05-26     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  England    
Other Details:
Languages:  eng     Pagination:  F276-7     Citation Subset:  AIM; IM    
Paediatric Service, Unitat de Recerca Infància i Enton, Hospital del Mar, Paseo Marítimo 25-29, 08003 Barcelona, Spain.
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MeSH Terms
Areca / adverse effects,  toxicity*
Arecoline / analysis
Infant, Newborn
Maternal-Fetal Exchange
Meconium / chemistry
Neonatal Abstinence Syndrome / etiology
Placenta / chemistry,  pathology
Pregnancy Outcome*
Prenatal Exposure Delayed Effects*
Reg. No./Substance:

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