Document Detail

Prenatal evaluation and in utero platelet transfusion for thrombocytopenia absent radii syndrome.
MedLine Citation:
PMID:  7845901     Owner:  NLM     Status:  MEDLINE    
A fetus with absent radii in both forearms was discovered on routine ultrasound examination performed at 18 weeks of pregnancy. No other significant abnormalities were found, and no signs of haemorrhage were detected. Serial ultrasound examinations revealed no evidence of fetal internal bleeding. At 37 weeks of pregnancy, a CBC obtained by cordocentesis under ultrasound guidance confirmed the diagnosis of thrombocytopenia absent radii (TAR) syndrome. Apheresis platelets were transfused into the umbilical vein to correct the thrombocytopenia and was followed by an uncomplicated delivery. No bleeding was encountered during the remainder of the baby's neonatal course. We conclude that TAR syndrome can be readily identified prenatally on sonogram, and if severe thrombocytopenia is confirmed by cordocentesis, platelets should be transfused to diminish the risk of serious internal bleeding during and immediately after delivery.
M Weinblatt; B Petrikovsky; M Bialer; J Kochen; R Harper
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  14     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  1994 Sep 
Date Detail:
Created Date:  1995-03-08     Completed Date:  1995-03-08     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  892-6     Citation Subset:  IM    
Cornell University Medical College, Division of Pediatric Hematology, Manhasset, NY.
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MeSH Terms
Blood Transfusion, Intrauterine / standards*
Congenital Abnormalities / diagnosis,  ultrasonography
Fetal Diseases / diagnosis,  therapy*,  ultrasonography
Platelet Transfusion / standards*
Pregnancy Trimester, Second
Prenatal Diagnosis*
Radius / abnormalities*
Thrombocytopenia / diagnosis,  therapy*,  ultrasonography
Ultrasonography, Prenatal

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