Document Detail

Prenatal dopamine and neonatal behavior and biochemistry.
MedLine Citation:
PMID:  18774177     Owner:  NLM     Status:  MEDLINE    
Depressed pregnant women (N=126) were divided into high and low prenatal maternal dopamine (HVA) groups based on a tertile split on their dopamine levels at 20 weeks gestation. The high versus the low dopamine group had lower Center for Epidemiological Studies-Depression Scale (CES-D) scores, higher norepinephrine levels at the 20-week gestational age visit and higher dopamine and serotonin levels at both the 20- and the 32-week gestational age visits. The neonates of the mothers with high versus low prenatal dopamine levels also had higher dopamine and serotonin levels as well as lower cortisol levels. Finally, the neonates in the high dopamine group had better autonomic stability and excitability scores on the Brazelton Neonatal Behavior Assessment Scale. Thus, prenatal maternal dopamine levels appear to be negatively related to prenatal depression scores and positively related to neonatal dopamine and behavioral regulation, although these effects are confounded by elevated serotonin levels.
Tiffany Field; Miguel Diego; Maria Hernandez-Reif; Barbara Figueiredo; Osvelia Deeds; Angela Ascencio; Saul Schanberg; Cynthia Kuhn
Related Documents :
14561127 - Prospective relations between rejection and depression in young adolescents.
24555047 - Internet-delivered eye movement desensitization and reprocessing (iemdr): an open trial.
24373987 - Hypocretin in cerebrospinal fluid is positively correlated with tau and ptau.
20059307 - Depressive disorders among adolescents managed in a child and adolescent mental health ...
18308817 - Clozapine-induced myocarditis after long-term treatment: case presentation and clinical...
11142437 - Risperidone in treating behavioural disturbances of prader-willi syndrome.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't     Date:  2008-09-05
Journal Detail:
Title:  Infant behavior & development     Volume:  31     ISSN:  1934-8800     ISO Abbreviation:  Infant Behav Dev     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-10     Completed Date:  2009-08-11     Revised Date:  2013-06-05    
Medline Journal Info:
Nlm Unique ID:  7806016     Medline TA:  Infant Behav Dev     Country:  United States    
Other Details:
Languages:  eng     Pagination:  590-3     Citation Subset:  IM    
Touch Research Institutes, University of Miami Medical School, Miami, FL 33101, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Depressive Disorder / diagnosis,  psychology,  urine
Infant Behavior / physiology*,  psychology*
Infant, Newborn
Pregnancy Complications / psychology*,  urine*
Prenatal Care / methods
Prenatal Exposure Delayed Effects / psychology*,  urine*
Young Adult
Grant Support
AT 001585/AT/NCCAM NIH HHS; AT 00370/AT/NCCAM NIH HHS; K05 AT001585-03/AT/NCCAM NIH HHS; K05 MH000331-21/MH/NIMH NIH HHS; MH 0033 1/MH/NIMH NIH HHS; MH 46586/MH/NIMH NIH HHS; R01 AT000370-06/AT/NCCAM NIH HHS; R37 MH046586-11/MH/NIMH NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Infant responses to maternal still-face at 4 and 9 months.
Next Document:  Odorization of a novel object can influence infant's exploratory behavior in unexpected ways.