| Prenatal diagnosis of a (X;X) translocation by fluorescence in situ hybridization and laser scanning image cytometry. | |
| | |
MedLine Citation:
|
PMID: 8579777 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
A de novo structural abnormality of one X chromosome was prenatally detected in a female fetus. This chromosomal abnormality has been analyzed by conventional cytogenetic methods, fluorescence in situ hybridization, and laser scanning image cytometry. The association of these techniques has demonstrated that this anomaly corresponds to a (X;X) translocation. Analysis of hybridization signals by laser scanning image cytometry allowed to localize that the breakpoints were at the X-centromeric region and Xp11.3, respectively. These results show the usefulness of image analysis and fluorescence in situ hybridization for a rapid characterization of de novo structural chromosome anomalies in prenatal diagnosis. |
| | |
Authors:
|
G Tachdjian; V Cacheux; H Kiefer; L Druart; J M Lapierre; J F Oury; P Blot; P Metezeau |
Related Documents
:
|
21523337 - Coexistence of inversion 16 and the philadelphia chromosome comprising p190 bcr/abl in ... 21461697 - How to be a mitotic chromosome. 21115657 - The three vibrio cholerae chromosome ii-encoded pare toxins degrade chromosome i follow... 12239727 - Diploid/tetraploid/t(1;6) mosaicism in a 17-year-old female with hypomelanosis of ito, ... 14635607 - Hla cw3 and hla cw4 have a protective effect on acquisition of chronic myeloid leukemia... 16093727 - Linkage disequilibrium inflates type i error rates in multipoint linkage analysis when ... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Fetal diagnosis and therapy Volume: 10 ISSN: 1015-3837 ISO Abbreviation: Fetal. Diagn. Ther. Publication Date: 1995 Nov-Dec |
Date Detail:
|
Created Date: 1996-03-19 Completed Date: 1996-03-19 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 9107463 Medline TA: Fetal Diagn Ther Country: SWITZERLAND |
Other Details:
|
Languages: eng Pagination: 387-92 Citation Subset: IM |
Affiliation:
|
Unité de Cytogénétique, Hôpital Robert-Debré, Paris, France. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Female Humans Image Cytometry* In Situ Hybridization, Fluorescence* Pregnancy Prenatal Diagnosis / methods* Sex Chromosome Aberrations / diagnosis*, genetics Translocation, Genetic / genetics* X Chromosome / genetics* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Cardiac defects in 1st-trimester fetuses with trisomy 18.
Next Document: Congenital diaphragmatic hernia: prognosis and prenatal detection.