Document Detail

Prenatal diagnosis of tracheal obstruction: possible association with maternal pertussis infection.
MedLine Citation:
PMID:  10776017     Owner:  NLM     Status:  MEDLINE    
A fetus with the sonographic appearance of echogenic and enlarged lungs and dilated trachea and bronchi, indicating laryngotracheal obstruction, is reported. Additionally, the fetus had ascites and subcutaneous edema and the amniotic fluid volume was reduced. Doppler flow investigation of the systemic venous circulation revealed signs of heart failure, and color Doppler visualized possible increased pulmonary flow. Following termination of pregnancy, autopsy confirmed the sonographic observations and revealed a hypoplastic thymus. During the present pregnancy the mother suffered from sustained cough, and serological tests revealed acute pertussis infection. Polymerase chain reaction investigation for Bordetella pertussis in the amniotic fluid was negative. The possibilities of pertussis toxins as noxious factors and of an atypical presentation of DiGeorge anomaly are discussed.
G Haugen; P A Jenum; D Scheie; S Sund; B Stray-Pedersen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  15     ISSN:  0960-7692     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2000 Jan 
Date Detail:
Created Date:  2000-05-25     Completed Date:  2000-05-25     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  69-73     Citation Subset:  IM    
Department of Obstetrics and Gynecology, National Hospital, University of Oslo, Norway.
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MeSH Terms
Abortion, Therapeutic
Acute Disease
Airway Obstruction / congenital,  microbiology*,  pathology,  ultrasonography*
Fetal Diseases / microbiology*,  pathology,  ultrasonography*
Hydrops Fetalis / ultrasonography
Infectious Disease Transmission, Vertical*
Lymphatic Diseases / pathology,  ultrasonography
Pregnancy Complications, Infectious* / blood,  immunology
Thymus Gland / pathology,  ultrasonography
Tracheobronchomegaly / microbiology*,  pathology,  ultrasonography*
Ultrasonography, Doppler, Color / methods*
Ultrasonography, Prenatal / methods*
Whooping Cough / blood,  congenital*,  immunology,  transmission*

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