Document Detail


Prenatal diagnosis and therapy for a fetal hepatic vascular malformation.
MedLine Citation:
PMID:  7724135     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Congenital hepatic arteriovenous malformations complicated by high-output heart failure and hematologic derangements are associated with up to 90% mortality. Prenatal diagnosis alerts the pediatrician to the need for early neonatal intervention. CASE: A fetal hepatic arteriovenous malformation with associated high-output cardiac failure was diagnosed at 29 weeks' gestation using real-time and color flow Doppler sonography. Hydrocortisone injected directly into the umbilical vein and the amniotic sac resulted in appreciable improvement in hemodynamic and hematologic indices. The pregnancy ended in a preterm delivery at 31 weeks with no evidence of heart failure at birth. CONCLUSION: The compromised preterm fetus with a hepatic arteriovenous malformation can be treated in utero, avoiding early emergency delivery.
Authors:
A A Mejides; A M Adra; M J O'Sullivan; M C Nicholas
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  85     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1995 May 
Date Detail:
Created Date:  1995-05-22     Completed Date:  1995-05-22     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  850-3     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Miami School of Medicine, Florida, USA.
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MeSH Terms
Descriptor/Qualifier:
Angiography
Arteriovenous Malformations* / drug therapy,  radiography,  ultrasonography
Cardiomegaly / ultrasonography
Echocardiography
Female
Hemangioma* / drug therapy,  radiography,  ultrasonography
Hepatic Artery / abnormalities*,  ultrasonography
Hepatic Veins / abnormalities*,  ultrasonography
Humans
Hydrocortisone / administration & dosage
Injections, Intravenous
Pregnancy
Ultrasonography, Doppler, Color
Ultrasonography, Doppler, Pulsed
Ultrasonography, Prenatal
Umbilical Veins
Chemical
Reg. No./Substance:
50-23-7/Hydrocortisone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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