Document Detail


Prenatal diagnosis of obstructive hydrocephalus associated with parvovirus B19 infection.
MedLine Citation:
PMID:  20664440     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Intrauterine parvovirus B19 infection is a well-known cause for hydrops fetalis and fetal demise. We present a case of isolated fetal obstructive hydrocephalus caused by an intrauterine parvovirus B19 infection. CASE: A 23-year-old woman, gravida 3 para 2, was referred for fetal obstructive hydrocephalus. Although there were no signs of fetal anemia, increased maternal parvovirus B19-specific immunoglobulin G and immunoglobulin M raised the suspicion of fetal infection. This was confirmed by polymerase chain reaction in the amniotic fluid. Elective cesarean delivery was performed at 34 weeks of gestation, followed by craniotomy and placement of shunt. At the age of 20 months, the child's development was in accordance with his age, with the exception of gross motor function, which was moderately delayed. CONCLUSION: Evaluation of fetal obstructive hydrocephalus should include maternal serological tests for parvovirus B19.
Authors:
Michal Zajicek; Liat Gindes; Chen Hoffmann; Iris Morag; Reuven Achiron
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  116 Suppl 2     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-28     Completed Date:  2010-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  521-2     Citation Subset:  AIM; IM    
Affiliation:
The Chaim Sheba Medical Center, Tel Hashomer, Israel. mic.zajicek@gmail.com
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MeSH Terms
Descriptor/Qualifier:
Female
Humans
Hydrocephalus / ultrasonography*,  virology*
Infant, Newborn
Male
Parvoviridae Infections / complications*,  virology
Parvovirus B19, Human
Pregnancy
Pregnancy Complications, Infectious*
Ultrasonography, Prenatal
Young Adult

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