Document Detail


Prenatal diagnosis in twin gestations.
MedLine Citation:
PMID:  22713497     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Twin gestations face an increased risk of structural abnormalities compared with singleton gestations, as well as an increased risk of aneuploidy. Accordingly, there is a need for accurate prenatal diagnosis of fetal genetic disorders and structural anomalies in twin gestations. Given the increased risk of congenital anomalies, a detailed sonographic survey of fetal anatomy is recommended in the early second trimester of twin gestations. In addition, fetal echocardiography should be considered in monochorionic twin gestations and in dichorionic twin pregnancies conceived using assisted reproductive technologies given the increased risk of congenital heart disease in these populations. Although first- and second-trimester aneuploidy screening in twin gestations is available, screening is less accurate than in singleton gestations. Invasive prenatal diagnosis in twin pregnancies is associated with a risk of pregnancy loss that is higher than the baseline risk of loss among twin gestations. Precise procedure-related loss rates in twin gestations undergoing chorionic villus sampling or amniocentesis, however, remain unclear because of methodological differences between published studies investigating diagnostic procedures in twins.
Authors:
Joy Vink; Ronald Wapner; Mary E D'Alton
Related Documents :
25388277 - Increasing maternal pre-pregnancy bmi is associated with reduced insulin sensitivity an...
20103457 - Evaluation of the phosphodiesterase 3 inhibitor org 9935 as a contraceptive in female m...
3240777 - Fertility in intersubspecific hybrids of laboratory mice (mus musculus domesticus) and ...
15624697 - Maternal tolerance to h-y is independent of il-10.
17461797 - Nuclear functions of the arf guanine nucleotide exchange factor brag2.
10601087 - Selection of good embryos for transfer depends on embryo cohort size: implications for ...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Seminars in perinatology     Volume:  36     ISSN:  1558-075X     ISO Abbreviation:  Semin. Perinatol.     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-20     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7801132     Medline TA:  Semin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  169-74     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Division of Maternal Fetal Medicine, Department of OB/GYN, Columbia University Medical Center, New York, NY.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Effects of twin gestation on maternal morbidity.
Next Document:  Fetal growth disorders in twin gestations.