Document Detail


[Prenatal diagnosis of hyperechogenic kidneys: A study of 17 cases].
MedLine Citation:
PMID:  20832953     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To evaluate the prenatal diagnosis and the prognostic value of ultrasound in case of fetal hyperechogenic kidneys.
PATIENTS AND METHODS: Seventeen prenatally diagnosed cases of hyperechogenic kidneys were retrospectively reviewed at the University Hospital of Lille from 1997 to 2008. The clinical and ultrasound data were compared to the postnatal follow-up and the long-term prognosis.
RESULTS: The aetiologies are nine recessive polycystic kidney diseases, three dominant, two Bardet-Biedl syndromes and three cases of transient renal hyperechogenicity. No renal ultrasonographic criterion is specific of aetiology. Five pregnancies were terminated. We observed one neonatal death and 11 survivors (median follow-up: 30months) including two infants with hypertension. All oligohydramnios (n=8) were associated with poor prenatal outcomes (terminations of pregnancy, neonatal death or hypertension) compared to the other nine with normal amniotic fluid volume (nine children symptom-free). Kidneys less or equal to +4 S.D. and a normal amniotic fluid volume were associated with a good prognosis (n=7, seven symptom-free).
CONCLUSION: The fetal kidneys characteristics on prenatal ultrasound fail to provide an accurate etiological diagnosis. Only congenital defects and family history adjust the aetiology. Amniotic fluid volume and fetal kidney size are the best prenatal predictors of outcome.
Authors:
V Emmanuelli; A Lahoche-Manucci; M Holder-Espinasse; L Devisme; P Vaast; A Dieux-Coeslier; M Dehennault; S Petit; R Besson; V Houfflin-Debarge
Publication Detail:
Type:  Case Reports; English Abstract; Journal Article     Date:  2010-09-15
Journal Detail:
Title:  Journal de gynécologie, obstétrique et biologie de la reproduction     Volume:  39     ISSN:  1773-0430     ISO Abbreviation:  J Gynecol Obstet Biol Reprod (Paris)     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-26     Completed Date:  2011-03-11     Revised Date:  2014-08-12    
Medline Journal Info:
Nlm Unique ID:  0322206     Medline TA:  J Gynecol Obstet Biol Reprod (Paris)     Country:  France    
Other Details:
Languages:  fre     Pagination:  637-46     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Masson SAS. All rights reserved.
Vernacular Title:
Diagnostic anténatal des reins hyperéchogènes : à propos de 17 cas.
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MeSH Terms
Descriptor/Qualifier:
Bardet-Biedl Syndrome / embryology,  ultrasonography
Female
Gestational Age
Humans
Kidney / embryology*,  ultrasonography*
Kidney Diseases / embryology*,  ultrasonography*
Oligohydramnios
Polycystic Kidney Diseases / embryology,  genetics,  ultrasonography
Pregnancy
Pregnancy Outcome
Prognosis
Ultrasonography, Prenatal*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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